DDX56 and SOX30

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		DDX56	SOX30
Description		DEAD-box helicase 56	SRY-box transcription factor 30
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytosol Membrane	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Chromocenter
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity RNA Stem-loop Binding Protein Sequestering Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Beta-catenin Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cytoplasmic Pattern Recognition Receptor Signaling Pathway RRNA Processing Protein Import Into Nucleus Positive Regulation Of Neuron Projection Development Negative Regulation Of Type I Interferon Production Ribosome Biogenesis Host-mediated Perturbation Of Viral RNA Genome Replication Defense Response To Virus	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Spermatid Development Negative Regulation Of Wnt Signaling Pathway Response To Corticosteroid Positive Regulation Of Transcription By RNA Polymerase II Proacrosomal Vesicle Fusion
Pathways
Drugs
Diseases
GWAS		LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)	Glycated hemoglobin levels ( 28898252) Triglyceride levels ( 31647587)
Interacting Genes		6 interacting genes: EHD2 EIF4A3 OGT SOX30 USP33 ZNF408	18 interacting genes: AHCYL1 AURKA BAMBI BRCA1 CFAP206 CUL5 DCAF4 DDX56 FBXO38 FHL2 FLI1 GNAI3 GP2 KIFC3 NME1 NUDT3 PAXIP1 TRAF2
Entrez ID		54606	11063
HPRD ID		12154	09461
Ensembl ID		ENSG00000136271	ENSG00000039600
Uniprot IDs		Q9NY93	B4DXW7 O94993
PDB IDs			7JJK
Enriched GO Terms of Interacting Partners?		Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Selenocysteine Incorporation Cellular Response To Selenite Ion Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Negative Regulation Of Translation Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Translation Protein O-acetylglucosaminyltransferase Activity Selenocysteine Insertion Sequence Binding Negative Regulation Of Translational Elongation Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Regulation Of Translation At Postsynapse Proacrosomal Vesicle Fusion VCB Complex
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