ZBTB48 and UPF2

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		ZBTB48	UPF2
Gene Name		zinc finger and BTB domain containing 48	UPF2 regulator of nonsense transcripts homolog (yeast)
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Cytoplasm Cytosol Exon-exon Junction Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Liver Development MRNA Export From Nucleus Gene Expression Organ Regeneration
Pathways			Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions		17 interactors: C11orf58 C7orf34 CDK2AP2 CDKN1A DVL3 EP300 GPATCH2L ILK KRTAP10-5 NME7 NUDT21 PNRC2 RGS2 TNFRSF14 UPF2 ZBTB7A ZBTB8A	75 interactors: ABCF2 AGPAT1 ART4 ATP1B3 BLM CALR CENPU CIZ1 COMTD1 CYBA DCP1B DCP2 DPF2 E4F1 EIF1 EIF4A1 EIF4G1 ENO1 EXOSC1 EXOSC10 EXOSC4 EXOSC6 EXOSC8 GADD45GIP1 GLTSCR2 HBZ HMGA1 HS3ST3A1 HSF2BP ITGB1 KRT18 LDHA LSM1 MAP1A MAP1LC3B MIF MRPL40 MTERF3 MYB NDUFA7 NOB1 NOMO1 PHB2 PITX1 PUF60 RNPS1 RPL13 RPL5 RPL8 RPS15 RPS25 RPS6 RPS7 RRP7A RSRC2 SERBP1 SERF2 SKIV2L2 SMG1 SUMO3 TK1 TNNI2 TOP3B TUBB2A TYMS UPF1 UPF3B WNK1 XRN1 XRN2 ZBTB48 ZFP36 ZGPAT ZNF408 ZNF44
Entrez ID		3104	26019
HPRD ID		01316	10405
Ensembl ID		ENSG00000204859	ENSG00000151461
Uniprot IDs		A8K291 B2R702 P10074	Q9HAU5
PDB IDs		3B84	1UW4 2WJV
Enriched GO Terms of Interacting Partners?		Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Protein Kinase Activity Negative Regulation Of Transferase Activity Regulation Of Protein Metabolic Process Cellular Response To Heat Histone H2B Acetylation Negative Regulation Of Protein Phosphorylation Regulation Of Kinase Activity Cell Aging Organ Regeneration Regulation Of Phosphorus Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Negative Regulation Of Phosphorylation Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process N-terminal Peptidyl-lysine Acetylation Response To Heat Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Kinase Activity G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Kinase Activity Positive Regulation Of Cytokine Secretion Involved In Immune Response Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Tubulin Deacetylation Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Intestinal Epithelial Cell Maturation Non-canonical Wnt Signaling Pathway Via JNK Cascade MRNA Metabolic Process Cell Cycle Arrest Nuclear-transcribed MRNA Catabolic Process Organ Development Positive Regulation Of Transferase Activity Positive Regulation Of Wnt Signaling Pathway Developmental Process Regulation Of Adrenergic Receptor Signaling Pathway	Nuclear-transcribed MRNA Catabolic Process RNA Catabolic Process MRNA Catabolic Process Aromatic Compound Catabolic Process MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Macromolecule Catabolic Process Gene Expression Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay RRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Catabolic Process Histone MRNA Catabolic Process RRNA Processing Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Translational Initiation Viral Process Ribosome Biogenesis Biosynthetic Process Histone MRNA Metabolic Process Cellular Metabolic Process Translational Termination Protein Complex Disassembly Translational Elongation RNA Biosynthetic Process Ribonucleoprotein Complex Biogenesis Cellular Protein Complex Disassembly Viral Transcription NcRNA Metabolic Process SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Viral Life Cycle Cytoplasmic Transport Metabolic Process Establishment Of Protein Localization To Membrane Translation Protein Targeting To Membrane Nuclear MRNA Surveillance Protein Localization To Membrane
Tagcloud ?			achieves bridge cenp centromere centromeres counteracted decay delocalization dispensable ebs1 extragenic fission interphase massive mis16 mis18 mis19 mis20 missegregation pombe recruiting schizosaccharomyces segregation sense snf snf22 snf5 sol1 swi
Tagcloud (Difference) ?			achieves bridge cenp centromere centromeres counteracted decay delocalization dispensable ebs1 extragenic fission interphase massive mis16 mis18 mis19 mis20 missegregation pombe recruiting schizosaccharomyces segregation sense snf snf22 snf5 sol1 swi
Tagcloud (Intersection) ?