ZBTB48 and TNFRSF14

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ZBTB48	TNFRSF14
Gene Name		zinc finger and BTB domain containing 48	tumor necrosis factor receptor superfamily, member 14
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding	Virus Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Positive Regulation Of Cytokine Secretion Involved In Immune Response Immune Response Cell Surface Receptor Signaling Pathway Response To Virus Viral Process T Cell Costimulation Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Alpha-beta T Cell Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Regulation Of T Cell Migration
Pathways			Costimulation by the CD28 family Adaptive Immune System
Drugs
Diseases
GWAS			Celiac disease ( 20190752) Rheumatoid arthritis ( 18794853 20453842) Ulcerative colitis ( 23128233 21297633)
Protein-Protein Interactions		17 interactors: C11orf58 C7orf34 CDK2AP2 CDKN1A DVL3 EP300 GPATCH2L ILK KRTAP10-5 NME7 NUDT21 PNRC2 RGS2 TNFRSF14 UPF2 ZBTB7A ZBTB8A	30 interactors: A2M APP BTLA CD160 CHD3 DGKD DRAP1 DYNLL1 ESR1 HDAC3 HDAC4 IMPA2 ITFG1 KIAA1377 LTA MBTPS1 NDUFS2 NRIP1 RAD21 SERPINA4 TNFSF13 TNFSF14 TRAF1 TRAF2 TRAF3 TRAF5 UBQLN4 VIM WDR73 ZBTB48
Entrez ID		3104	8764
HPRD ID		01316	04122
Ensembl ID		ENSG00000204859	ENSG00000157873
Uniprot IDs		A8K291 B2R702 P10074	Q92956
PDB IDs		3B84	1JMA 2AW2 4FHQ
Enriched GO Terms of Interacting Partners?		Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Protein Kinase Activity Negative Regulation Of Transferase Activity Regulation Of Protein Metabolic Process Cellular Response To Heat Histone H2B Acetylation Negative Regulation Of Protein Phosphorylation Regulation Of Kinase Activity Cell Aging Organ Regeneration Regulation Of Phosphorus Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Negative Regulation Of Phosphorylation Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process N-terminal Peptidyl-lysine Acetylation Response To Heat Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Kinase Activity G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Kinase Activity Positive Regulation Of Cytokine Secretion Involved In Immune Response Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Tubulin Deacetylation Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Intestinal Epithelial Cell Maturation Non-canonical Wnt Signaling Pathway Via JNK Cascade MRNA Metabolic Process Cell Cycle Arrest Nuclear-transcribed MRNA Catabolic Process Organ Development Positive Regulation Of Transferase Activity Positive Regulation Of Wnt Signaling Pathway Developmental Process Regulation Of Adrenergic Receptor Signaling Pathway	Signal Transduction Apoptotic Process Programmed Cell Death Signaling Cell Communication Cell Death Death Cellular Response To Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Process Response To Stimulus Regulation Of Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Proteolysis Regulation Of Nitrogen Compound Metabolic Process Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Immune Response Regulation Of Endopeptidase Activity Regulation Of Immune System Process Regulation Of Peptidase Activity Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Protein Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription Factor Import Into Nucleus Response To Stress Negative Regulation Of Endopeptidase Activity Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Peptidase Activity Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cell Activation Histone H4 Deacetylation Positive Regulation Of NF-kappaB Transcription Factor Activity Spindle Organization Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Immune System Process Immune System Process Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Protein Binding Negative Regulation Of Proteolysis Positive Regulation Of Adaptive Immune Response Positive Regulation Of Immunoglobulin Mediated Immune Response Histone H3 Deacetylation Negative Regulation Of Protein Processing Regulation Of Transcription From RNA Polymerase II Promoter Histone H3-K9 Modification Regulation Of Establishment Of Protein Localization
Tagcloud ?			aberrations additional advances approaches biological closely contribute crebbp ep300 epha7 expected ezh2 fl follicular genetic hallmark hand individuals lymphoma mef2b microenvironment mll2 pathogenesis recognized recurrent technology translocation understanding unique
Tagcloud (Difference) ?			aberrations additional advances approaches biological closely contribute crebbp ep300 epha7 expected ezh2 fl follicular genetic hallmark hand individuals lymphoma mef2b microenvironment mll2 pathogenesis recognized recurrent technology translocation understanding unique
Tagcloud (Intersection) ?