MTF2 and SUV39H2

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		MTF2	SUV39H2
Gene Name		metal response element binding transcription factor 2	suppressor of variegation 3-9 homolog 2 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm ESC/E(Z) Complex	Chromosome, Centromeric Region Chromatin Nucleoplasm Nuclear Heterochromatin
	Molecular Function	DNA Binding Zinc Ion Binding Methylated Histone Binding	Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific)
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Segment Specification Gene Expression Chromatin Modification Stem Cell Maintenance Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription From RNA Polymerase II Promoter Stem Cell Differentiation Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Assembly Or Disassembly Chromatin Remodeling Transcription, DNA-templated Male Meiosis Cell Differentiation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways		Epigenetic regulation of gene expression PRC2 methylates histones and DNA	Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CREB1 GPRASP1 GSK3B KDM1A PRKD2 PRMT6 SMAD3 SUV39H1 SUV39H2 TMED9	39 interactors: AKAP9 APPL2 BLZF1 C8orf74 CBX5 CBX7 CCDC151 CCDC37 CDCA4 CEP70 CGGBP1 EWSR1 FAM20C GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MCM3AP MRFAP1 MTF2 MYL12A NME4 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		22823	79723
HPRD ID		14342	07580
Ensembl ID		ENSG00000143033	ENSG00000152455
Uniprot IDs		B4DZ69 B4DZG1 Q7Z534 Q96G26 Q9Y483	Q9H5I1
PDB IDs			2R3A
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Biosynthetic Process Histone H3-K9 Dimethylation Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Rhythmic Process Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Histone Modification Positive Regulation Of Organelle Organization Histone Methylation Regulation Of Organelle Organization Peptidyl-amino Acid Modification Negative Regulation Of Circadian Rhythm Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone H3-K9 Methylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Protein Methylation Regulation Of RNA Metabolic Process Peptidyl-lysine Trimethylation Viral Process Cellular Response To Growth Factor Stimulus Cellular Protein Modification Process Response To Growth Factor Chromatin Modification Regulation Of Gene Expression, Epigenetic Histone H3-K9 Modification Regulation Of Immune System Process Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Response To Stress Transcription, DNA-templated Regulation Of Binding Chromatin Organization RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell-matrix Adhesion Cellular Response To Stress Positive Regulation Of Gene Expression Response To Hypoxia Pituitary Gland Development Positive Regulation Of Stem Cell Differentiation Protein Metabolic Process	Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Cellular Process Positive Regulation Of Histone H3-K27 Methylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Histone H3-K27 Methylation Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Osteoblast Differentiation Biosynthetic Process Regulation Of Epidermal Growth Factor-activated Receptor Activity Golgi To Plasma Membrane Transport Positive Regulation Of Histone Methylation Nitrogen Compound Metabolic Process Positive Regulation Of DNA Metabolic Process Osteoclast Maturation Regulation Of Histone Methylation Regulation Of Ossification Protein Targeting Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription, DNA-templated Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process Establishment Of Protein Localization To Membrane Positive Regulation Of DNA Replication Positive Regulation Of Histone Modification Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Osteoblast Differentiation Myeloid Cell Differentiation Negative Regulation Of Gene Expression, Epigenetic Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Protein Localization To Plasma Membrane Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition
Tagcloud ?		aebp2 biotap c10orf12 c17orf96 cbx4 connecting disrupt eed ehmt1 exclusive fail interactors iterative jarid2 mutually phf1 prc1 prc2 preservation pulldowns reciprocal repressive seq suz12 tagged unexpected validate validating xl	a7 circular dichroism dim g12 g13 g9a h3k9 h3k9me0 h3k9me1 h3k9me2 h3k9me3 introduce introduces k14 labrador n324k pkmts prefers processive r8 readout recognizes renders retrievers s10 t11 t6
Tagcloud (Difference) ?		aebp2 biotap c10orf12 c17orf96 cbx4 connecting disrupt eed ehmt1 exclusive fail interactors iterative jarid2 mutually phf1 prc1 prc2 preservation pulldowns reciprocal repressive seq suz12 tagged unexpected validate validating xl	a7 circular dichroism dim g12 g13 g9a h3k9 h3k9me0 h3k9me1 h3k9me2 h3k9me3 introduce introduces k14 labrador n324k pkmts prefers processive r8 readout recognizes renders retrievers s10 t11 t6
Tagcloud (Intersection) ?