SAP130 and CCR9

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		SAP130	CCR9
Description		Sin3A associated protein 130	C-C motif chemokine receptor 9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Speck Sin3-type Complex	Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane
	Molecular Function		G Protein-coupled Receptor Activity Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways		HATs acetylate histones NoRC negatively regulates rRNA expression	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs			Vercirnon
Diseases
GWAS		Anti-saccade response ( 29064472) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Celiac disease ( 20190752) Liver enzyme levels (alkaline phosphatase) ( 33972514) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)
Interacting Genes		7 interacting genes: ARID4B CCR9 CUL2 GPS1 MYC SMAD3 USP7	19 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TRPM4 TSPAN7 TTYH1 YWHAE
Entrez ID		79595	10803
HPRD ID		18015	09200
Ensembl ID		ENSG00000136715	ENSG00000173585
Uniprot IDs		A0A2R8YDB8 H7BXF5 Q96DP1 Q9H0E3	B2R734 P51686
PDB IDs			5LWE
Enriched GO Terms of Interacting Partners?		Nucleoplasm Chromatin Remodeling Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Intracellular Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Organization MAPK Cascade Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Positive Regulation Of MiRNA Transcription JNK Cascade Positive Regulation Of MiRNA Metabolic Process Regulation Of Intracellular Transport Epigenetic Regulation Of Gene Expression Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ubiquitin Protein Ligase Binding Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of MiRNA Transcription T Cell Activation Regulation Of Stem Cell Population Maintenance Myc-Max Complex Regulation Of Acinar Cell Proliferation Regulation Of Cellular Response To Growth Factor Stimulus Sterol Response Element Binding Regulation Of MiRNA Metabolic Process Paraxial Mesoderm Morphogenesis Cis-regulatory Region Sequence-specific DNA Binding Apoptotic Signaling Pathway NK T Cell Proliferation Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Symbiont-mediated Disruption Of Host Cell PML Body CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation	Regulation Of T Cell Cytokine Production Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Regulation Of T Cell Mediated Immunity
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