SAP130 and ARID4B

Number of citations of the paper that reports this interaction (PMID 12724404)
52

Data Source:
HPRD (in vitro)

		SAP130	ARID4B
Gene Name		Sin3A-associated protein, 130kDa	AT rich interactive domain 4B (RBP1-like)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm STAGA Complex	Cellular_component Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Transcription Coactivator Activity Histone Acetyltransferase Activity	Molecular_function Protein Binding Transcription Regulatory Region DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Gene Expression Regulation Of Gene Expression, Epigenetic Histone H3 Acetylation Negative Regulation Of Gene Expression, Epigenetic	Chromatin Organization Regulation Of Gene Expression By Genetic Imprinting Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Spermatogenesis Biological_process Gene Expression Histone H4-K20 Trimethylation Histone H3-K9 Trimethylation Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription From RNA Polymerase II Promoter Establishment Of Sertoli Cell Barrier
Pathways		NoRC negatively regulates rRNA expression Chromatin modifying enzymes Chromatin organization Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression HATs acetylate histones	NoRC negatively regulates rRNA expression Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ARID4B CSN1S1 CUL2 MYC SMAD3	4 interactors: ETS1 RANBP2 SAP130 SIN3A
Entrez ID		79595	51742
HPRD ID		18015	10661
Ensembl ID		ENSG00000136715	ENSG00000054267
Uniprot IDs		Q9H0E3	Q4LE39
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Arrest Negative Regulation Of Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Cell Proliferation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Positive Regulation Of Cysteine-type Endopeptidase Activity Mesonephros Development Positive Regulation Of Endopeptidase Activity Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Peptidase Activity Fibroblast Apoptotic Process Kidney Epithelium Development Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cell Cycle Evasion Or Tolerance Of Host Defenses By Virus Response To Transforming Growth Factor Beta Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Programmed Cell Death Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression, Epigenetic Cell Cycle Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Cell Death Death Epithelium Development DNA-templated Transcription, Initiation Response To Abiotic Stimulus Regulation Of Extracellular Matrix Assembly Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Establishment Of Sertoli Cell Barrier Primary MiRNA Processing Negative Regulation Of Monocyte Differentiation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Cell Proliferation Involved In Kidney Development Regulation Of Epithelial Cell Proliferation Positive Regulation Of Proteolysis Response To Hypoxia SMAD Protein Complex Assembly Negative Regulation Of Osteoblast Proliferation Histone H4-K20 Trimethylation Negative Regulation Of Gene Expression	Cellular Glucose Homeostasis Negative Regulation Of Gene Expression, Epigenetic RNA Biosynthetic Process Nucleus Organization Response To Methylglyoxal Negative Regulation Of Histone H3-K27 Acetylation Organelle Organization RNA Metabolic Process Cellular Response To Oxidative Stress Glucose Homeostasis Regulation Of Gene Expression, Epigenetic Gene Expression Positive Regulation Of Chromatin Silencing Macromolecule Biosynthetic Process Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Peptidyl-lysine Modification PML Body Organization Negative Regulation Of Glucokinase Activity Nucleobase-containing Compound Metabolic Process Histone Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Response To Oxidative Stress Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Circadian Rhythm Response To Laminar Fluid Shear Stress Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Defense Response To Virus By Host Cellular Chemical Homeostasis Nitrogen Compound Metabolic Process Angiogenesis Involved In Wound Healing Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Transcription, DNA-templated Positive Regulation Of Erythrocyte Differentiation Negative Regulation Of Histone Acetylation Wound Healing Chromatin Modification Regulation Of Gene Silencing Negative Regulation Of Peptidyl-lysine Acetylation Hypothalamus Development Negative Regulation Of Protein Acetylation Regulation Of Transcription Regulatory Region DNA Binding Protein Sumoylation Response To Organic Substance Cellular Homeostasis
Tagcloud ?		clearance closure comprehensively dedifferentiate drastic edge enable fluorescently healing kismet mip120 modifying motile osa partly periphery practical publicly pvr reporter reporters repressed sin3a spt6 tagged tagging thirteen underlie wound
Tagcloud (Difference) ?		clearance closure comprehensively dedifferentiate drastic edge enable fluorescently healing kismet mip120 modifying motile osa partly periphery practical publicly pvr reporter reporters repressed sin3a spt6 tagged tagging thirteen underlie wound
Tagcloud (Intersection) ?