CCR9 and SCAMP4

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		CCR9	SCAMP4
Description		C-C motif chemokine receptor 9	secretory carrier membrane protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane	Membrane Trans-Golgi Network Membrane Recycling Endosome Membrane
	Molecular Function	G Protein-coupled Receptor Activity Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding	Protein Binding
	Biological Process	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Exocytosis Protein Transport
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs		Vercirnon
Diseases
GWAS		Celiac disease ( 20190752) Liver enzyme levels (alkaline phosphatase) ( 33972514) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)
Interacting Genes		19 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TRPM4 TSPAN7 TTYH1 YWHAE	17 interacting genes: ABHD6 AQP6 BIK CCR9 CGRRF1 CLDN7 CREB3 EBP EVI2B GPR152 KCNJ6 MDFI SLC10A1 SLC10A6 SPAG4 TMEM147 YAP1
Entrez ID		10803	113178
HPRD ID		09200	11536
Ensembl ID		ENSG00000173585	ENSG00000227500
Uniprot IDs		B2R734 P51686	Q969E2
PDB IDs		5LWE
Enriched GO Terms of Interacting Partners?		Regulation Of T Cell Cytokine Production Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Regulation Of T Cell Mediated Immunity	Bile Acid:sodium Symporter Activity Membrane
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