YIPF2 and PGRMC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YIPF2	PGRMC2
Description		Yip1 domain family member 2	progesterone receptor membrane component 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Trans Cisterna Endosome Golgi Apparatus Golgi Medial Cisterna Trans-Golgi Network Endomembrane System Membrane Transport Vesicle Late Endosome Membrane	Extracellular Region Nucleus Nuclear Envelope Nucleoplasm Endoplasmic Reticulum Endomembrane System Membrane Synapse Glutamatergic Synapse
	Molecular Function	Protein Binding Small GTPase Binding	Nuclear Steroid Receptor Activity Steroid Binding Protein Binding Lipid Binding Heme Transmembrane Transporter Activity Heme Binding
	Biological Process	Vesicle-mediated Transport	Heme Transport Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Adipose Tissue Development
Pathways			RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Heme signaling
Drugs
Diseases
GWAS			Bone mineral density (total hip) ( 29883787)
Interacting Genes		24 interacting genes: AQP6 CREB3 ERGIC3 FATE1 FFAR2 GPR42 HSD17B13 LEPROTL1 PGRMC2 RNF185 RNF5 SHISAL2A SLC10A6 SLC30A2 SLC39A3 SLC71A2 SPCS1 STING1 SYPL2 TMEM143 TMEM14B TMX2 TVP23B YIPF6	55 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LINC00632 LPAR3 MALL MFHAS1 ORMDL1 PEDS1-UBE2V1 PEX16 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VEZT YIPF2 ZDHHC21 ZFPL1
Entrez ID		78992	10424
HPRD ID		11332	09665
Ensembl ID		ENSG00000130733	ENSG00000164040
Uniprot IDs		K7ENM8 Q9BWQ6	O15173
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Ubiquitin-like Protein Conjugating Enzyme Binding Endoplasmic Reticulum Membrane Transmembrane Transport Endoplasmic Reticulum Mannose Trimming Protein Alpha-1,2-demannosylation Positive Regulation Of Type I Interferon-mediated Signaling Pathway Identical Protein Binding Protein Deglycosylation Zinc Ion Transmembrane Transporter Activity Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Endoplasmic Reticulum Quality Control Compartment Zinc Ion Transmembrane Transport Zinc Ion Transport CGAS/STING Signaling Pathway Nitrate Transmembrane Transporter Activity Monoatomic Ion Transport Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Positive Regulation Of Deacetylase Activity COPII-coated ER To Golgi Transport Vesicle Cyclic-di-GMP Binding STING Complex Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Pattern Recognition Receptor Signaling Pathway Golgi Membrane Regulation Of Type I Interferon-mediated Signaling Pathway Innate Immune Response-activating Signaling Pathway Mitochondrial Membrane PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Retrograde Transporter Complex, Golgi To ER 2',3'-cyclic GMP-AMP Binding Activation Of Innate Immune Response Mitochondrial Outer Membrane Protein Binding Monoatomic Cation Transport Positive Regulation Of Cytokine-mediated Signaling Pathway	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Myelination Axon Ensheathment Alkenylglycerophosphocholine Hydrolase Activity Compact Myelin
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