LAPTM5 and LDLRAD1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LAPTM5	LDLRAD1
Gene Name		lysosomal protein transmembrane 5	low density lipoprotein receptor class A domain containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Integral Component Of Plasma Membrane	Integral Component Of Membrane
	Molecular Function
	Biological Process	Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: ANKRD13A DCUN1D1 DISP1 EPN1 EPN2 EPN3 EPS15 HERC1 HEY1 HEYL HUWE1 ITCH KRT7 LDLRAD1 NEDD4 NEDD4L RNF168 SMURF2 TNFAIP3 TOM1L2 UBA52 UBAC1 UBC USP13 WWP1	16 interactors: BNIP3 BNIP3L GIMAP5 GPR128 LAPTM5 MAL MALL MARCH2 OLFM4 PLN PTTG1IP SLC1A1 TMEM147 TMEM190 TMEM218 VTI1B
Entrez ID		7805	388633
HPRD ID		03280	17372
Ensembl ID		ENSG00000162511
Uniprot IDs		Q13571 Q5TBB8	B7ZME3 Q5T700
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Notch Signaling Pathway Protein Catabolic Process Negative Regulation Of Signal Transduction Cellular Macromolecule Catabolic Process Negative Regulation Of Signaling Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Proteolysis Positive Regulation Of Protein Catabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein Monoubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Viral Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Protein Modification Process Viral Life Cycle Regulation Of ERBB Signaling Pathway Intracellular Receptor Signaling Pathway Negative Regulation Of Gene Expression Regulation Of Signal Transduction Negative Regulation Of Biosynthetic Process Catabolic Process Cellular Response To Stimulus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Type I Interferon Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein K63-linked Ubiquitination Regulation Of Signaling Cell Surface Receptor Signaling Pathway Signal Transduction	Mitochondrial Protein Catabolic Process Mitochondrial Outer Membrane Permeabilization Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Defense Response To Virus Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Transport Protein Homooligomerization Response To Virus Mitochondrial Membrane Organization Cysteine Transport Positive Regulation Of Interleukin-15 Production Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Cytotoxic T Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Calcium-transporting ATPase Activity TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Apoptotic Mitochondrial Changes Membrane Organization Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Negative Regulation Of Calcium Ion Binding Regulation Of The Force Of Heart Contraction By Cardiac Conduction Protein Oligomerization Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Membrane Raft Polarization Regulation Of Calcium-transporting ATPase Activity D-aspartate Import Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Membrane Raft Localization Negative Regulation Of Mitochondrial Fusion Granzyme-mediated Apoptotic Signaling Pathway Mitochondrial Transport Negative Regulation Of Calcium Ion Import Autophagic Cell Death Regulation Of Mitochondrial Fusion Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Cellular Response To Cobalt Ion Regulation Of Relaxation Of Cardiac Muscle Positive Regulation Of Cell Death Golgi To Vacuole Transport Negative Regulation Of ATPase Activity Regulation Of Relaxation Of Muscle Vesicle Fusion With Golgi Apparatus
Tagcloud ?		bioinformatics cd53 coeruleus ctss cx3cr1 degs downloaded encyclopedia enriched excision genomes glycan gse34516 hub idiopathic igsf6 ipd kyoto mismatch mortem omnibus ontology paired ppi ptprc slc5a7 spliceosome splicing transesterification
Tagcloud (Difference) ?		bioinformatics cd53 coeruleus ctss cx3cr1 degs downloaded encyclopedia enriched excision genomes glycan gse34516 hub idiopathic igsf6 ipd kyoto mismatch mortem omnibus ontology paired ppi ptprc slc5a7 spliceosome splicing transesterification
Tagcloud (Intersection) ?