LAPTM5 and TOM1L2

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LAPTM5	TOM1L2
Gene Name		lysosomal protein transmembrane 5	target of myb1-like 2 (chicken)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Integral Component Of Plasma Membrane	Intracellular Extracellular Vesicular Exosome
	Molecular Function		Protein Binding Protein Kinase Binding Clathrin Binding
	Biological Process	Transport	Intracellular Protein Transport Signal Transduction Negative Regulation Of Mitotic Nuclear Division
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: ANKRD13A DCUN1D1 DISP1 EPN1 EPN2 EPN3 EPS15 HERC1 HEY1 HEYL HUWE1 ITCH KRT7 LDLRAD1 NEDD4 NEDD4L RNF168 SMURF2 TNFAIP3 TOM1L2 UBA52 UBAC1 UBC USP13 WWP1	6 interactors: APP LAPTM5 MYO6 NEDD4 RNF11 UBC
Entrez ID		7805	146691
HPRD ID		03280	18213
Ensembl ID		ENSG00000162511	ENSG00000175662
Uniprot IDs		Q13571 Q5TBB8	B7Z2L7 B7Z2U2 F5H3S6 Q6ZVM7
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Notch Signaling Pathway Protein Catabolic Process Negative Regulation Of Signal Transduction Cellular Macromolecule Catabolic Process Negative Regulation Of Signaling Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Proteolysis Positive Regulation Of Protein Catabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein Monoubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Viral Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Protein Modification Process Viral Life Cycle Regulation Of ERBB Signaling Pathway Intracellular Receptor Signaling Pathway Negative Regulation Of Gene Expression Regulation Of Signal Transduction Negative Regulation Of Biosynthetic Process Catabolic Process Cellular Response To Stimulus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Type I Interferon Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein K63-linked Ubiquitination Regulation Of Signaling Cell Surface Receptor Signaling Pathway Signal Transduction	Synapse Organization Intracellular Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Abiotic Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Neuromuscular Junction Development Regulation Of DNA-templated Transcription In Response To Stress Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Synapse Assembly DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of ERBB Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Synapse Structure Or Activity Signal Transduction In Response To DNA Damage Intracellular Transport Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Cellular Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein Modification By Small Protein Conjugation Protein Catabolic Process Signal Transduction By P53 Class Mediator Endocytosis Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Notch Signaling Pathway Dendrite Development Establishment Of Localization In Cell Collateral Sprouting In Absence Of Injury Neuron Projection Development Protein Polyubiquitination Cellular Macromolecule Catabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Collateral Sprouting Axon Midline Choice Point Recognition Neuron Development Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Cellular Localization Regulation Of Cell Cycle Phase Transition Progesterone Receptor Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Locomotory Behavior Positive Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		bioinformatics cd53 coeruleus ctss cx3cr1 degs downloaded encyclopedia enriched excision genomes glycan gse34516 hub idiopathic igsf6 ipd kyoto mismatch mortem omnibus ontology paired ppi ptprc slc5a7 spliceosome splicing transesterification	becomes degradative endosomes enlarged fyn gat gga hepatocyte intermediary like1 like2 localizes multivesicular mvb mvbs myb1 p85 possesses ptap sorting stam tagged tsg101 ubiquitinated vhs vps27p
Tagcloud (Difference) ?		bioinformatics cd53 coeruleus ctss cx3cr1 degs downloaded encyclopedia enriched excision genomes glycan gse34516 hub idiopathic igsf6 ipd kyoto mismatch mortem omnibus ontology paired ppi ptprc slc5a7 spliceosome splicing transesterification	becomes degradative endosomes enlarged fyn gat gga hepatocyte intermediary like1 like2 localizes multivesicular mvb mvbs myb1 p85 possesses ptap sorting stam tagged tsg101 ubiquitinated vhs vps27p
Tagcloud (Intersection) ?