SLC35E3 and LNPEP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC35E3	LNPEP
Description		solute carrier family 35 member E3	leucyl and cystinyl aminopeptidase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Membrane	Extracellular Region Lysosomal Membrane Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Lumen Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleotide-sugar Transmembrane Transporter Activity Protein Binding Antiporter Activity	Aminopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding Metalloaminopeptidase Activity
	Biological Process	Organophosphate Ester Transport Nucleobase-containing Compound Transport Transmembrane Transport Carbohydrate Derivative Transport	Protein Polyubiquitination Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Proteolysis Cell-cell Signaling Female Pregnancy Regulation Of Blood Pressure Neuropeptide Catabolic Process Protein Catabolic Process Negative Regulation Of Cold-induced Thermogenesis
Pathways			Endosomal/Vacuolar pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) White blood cell count ( 20139978)	Acute anterior uveitis (with or without ankylosing spondylitis) ( 25200001) Ankylosing spondylitis ( 23749187) Birdshot chorioretinopathy ( 24957906) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233 28067908) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494)
Interacting Genes		23 interacting genes: ADIPOQ ARLN ATP6V0C BCL2L2 BIK BNIP2 CSGALNACT2 FAM209A FFAR2 FXYD6 GET1 GPR25 LNPEP PLP1 RUSF1 SELENOK SLC66A2 SPG21 SSMEM1 TMEM14B TMEM234 TMEM60 TTPA	37 interacting genes: AGT AQP6 ASGR2 BIK CD79A CGRRF1 CTAG1A CTAG1B CYB5R3 FAM210B FATE1 FCER1G FHOD1 FKBP7 GGT7 GPR42 GPX8 LCN2 LHFPL5 MMGT1 REEP4 REL SLC10A1 SLC2A4 SLC35E3 SLC39A9 SMAD9 SSMEM1 STOM TAS2R19 TCF4 TLCD4 TMEM35A TNKS TNKS2 UBQLN1 UNC93A
Entrez ID		55508	4012
HPRD ID		15375	01041
Ensembl ID		ENSG00000175782	ENSG00000113441
Uniprot IDs		Q7Z769	Q9UIQ6
PDB IDs			4P8Q 4PJ6 4Z7I 5C97 5JHQ 5MJ6 7ZYF 8CGP 8CGW 8P0I
Enriched GO Terms of Interacting Partners?		Membrane Bcl-2 Family Protein Complex Positive Regulation Of Chemokine Production Positive Regulation Of Monocyte Chemotactic Protein-1 Production	Membrane Positive Regulation Of Telomere Capping
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?