USP1 and PHF7

Number of citations of the paper that reports this interaction (PMID 23105109)
4

Data Source:
BioGRID (two hybrid)

		USP1	PHF7
Gene Name		ubiquitin specific peptidase 1	PHD finger protein 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Microtubule Organizing Center
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding	Zinc Ion Binding
	Biological Process	Skeletal System Development DNA Repair Regulation Of DNA Repair Response To UV Protein Deubiquitination Monoubiquitinated Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process
Pathways		Fanconi Anemia pathway Regulation of the Fanconi anemia pathway
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		9 interactors: DTX3 FANCD2 PCNA PHF7 PHLPP1 TRAF6 TRIM46 UBB UBC	15 interactors: APP ARIH2 DTX3L HIST3H3 IKBKG MDM2 RNF111 RNF14 RNF34 SRPK1 TRIM26 TRIM41 UBE2D4 USP1 USP15
Entrez ID		7398	51533
HPRD ID		04593	15127
Ensembl ID		ENSG00000162607	ENSG00000010318
Uniprot IDs		O94782	Q9BWX1 Q9NS08
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Fc Receptor Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway JNK Cascade Immune Response-regulating Cell Surface Receptor Signaling Pathway Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Viral Protein Processing Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Immune Response-regulating Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Antigen Receptor-mediated Signaling Pathway Notch Signaling Pathway Activation Of MAPK Activity Activation Of Innate Immune Response G1/S Transition Of Mitotic Cell Cycle Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Protein Ubiquitination Cellular Response To Growth Factor Stimulus Protein Polyubiquitination DNA Repair Response To Growth Factor Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Modification By Small Protein Conjugation Positive Regulation Of Innate Immune Response Cellular Response To Fibroblast Growth Factor Stimulus Notch Receptor Processing Response To Fibroblast Growth Factor Virion Assembly	Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Protein Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Protein K48-linked Ubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Polyubiquitination Protein Metabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Intracellular Receptor Signaling Pathway Cellular Macromolecule Catabolic Process Monoubiquitinated Protein Deubiquitination Regulation Of Proteolysis Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Innate Immune Response Negative Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Protein Metabolic Process Protein K63-linked Ubiquitination Proteolysis Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Stimulus Regulation Of Signal Transduction By P53 Class Mediator Response To Stress Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Endopeptidase Activity Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Negative Regulation Of Peptidase Activity Cellular Response To UV-C Cellular Response To Vitamin B1 Regulation Of Signal Transduction Immune Response Regulation Of Nitrogen Compound Metabolic Process Defense Response Negative Regulation Of Viral Process Response To Light Stimulus Negative Regulation Of Proteolysis Regulation Of Oxygen Metabolic Process Synaptic Growth At Neuromuscular Junction Histone H2B Conserved C-terminal Lysine Deubiquitination Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Tagcloud ?		bomb coimmunoprecipitation collated cytoskeleton defines depicts dissect evolutionarily fate fih hif1an interacted interesting mib mib2 mind notch protease ran screens summarized trabid traf ubiquitin ubiquitylate ubiquitylation usp9 zebrafish zranb1	ablates associates dimethyl drosophila ectopic eggs establishment exhibits finger gametogenesis germ germline h3k4me2 homologs identity male phd preference reader rescues sexual soma sperm spermatogenesis spermatogonia strikingly tails testis xx
Tagcloud (Difference) ?		bomb coimmunoprecipitation collated cytoskeleton defines depicts dissect evolutionarily fate fih hif1an interacted interesting mib mib2 mind notch protease ran screens summarized trabid traf ubiquitin ubiquitylate ubiquitylation usp9 zebrafish zranb1	ablates associates dimethyl drosophila ectopic eggs establishment exhibits finger gametogenesis germ germline h3k4me2 homologs identity male phd preference reader rescues sexual soma sperm spermatogenesis spermatogonia strikingly tails testis xx
Tagcloud (Intersection) ?