PHF7 and ARIH2

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		PHF7	ARIH2
Gene Name		PHD finger protein 7	ariadne RBR E3 ubiquitin protein ligase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Microtubule Organizing Center	Nucleus Cytoplasm
	Molecular Function	Zinc Ion Binding	Nucleic Acid Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process		Protein Polyubiquitination Multicellular Organismal Development Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Developmental Cell Growth Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Hematopoietic Stem Cell Proliferation
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		15 interactors: APP ARIH2 DTX3L HIST3H3 IKBKG MDM2 RNF111 RNF14 RNF34 SRPK1 TRIM26 TRIM41 UBE2D4 USP1 USP15	44 interactors: ARAP1 BUB1 CBR3 CCDC33 CUL5 DISC1 DLST EEF1A1 EEF1G EML4 ENSA IL4R KAT5 KCNQ2 KIAA1377 LOC147791 NEDD8 PHF7 PPP2R1A PTN REL RHEB RPL8 SCAMP2 SGCE SLC1A6 TP53 TRIM27 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2L3 UBE2L6 UBE2N UBE2R2 UBE2T UBE2V1 UGP2 UTP14A WDR91
Entrez ID		51533	10425
HPRD ID		15127	09286
Ensembl ID		ENSG00000010318	ENSG00000177479
Uniprot IDs		Q9BWX1 Q9NS08	O95376 Q6IBL8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Protein Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Protein K48-linked Ubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Polyubiquitination Protein Metabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Intracellular Receptor Signaling Pathway Cellular Macromolecule Catabolic Process Monoubiquitinated Protein Deubiquitination Regulation Of Proteolysis Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Innate Immune Response Negative Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Protein Metabolic Process Protein K63-linked Ubiquitination Proteolysis Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Stimulus Regulation Of Signal Transduction By P53 Class Mediator Response To Stress Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Endopeptidase Activity Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Negative Regulation Of Peptidase Activity Cellular Response To UV-C Cellular Response To Vitamin B1 Regulation Of Signal Transduction Immune Response Regulation Of Nitrogen Compound Metabolic Process Defense Response Negative Regulation Of Viral Process Response To Light Stimulus Negative Regulation Of Proteolysis Regulation Of Oxygen Metabolic Process Synaptic Growth At Neuromuscular Junction Histone H2B Conserved C-terminal Lysine Deubiquitination Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process	Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein K63-linked Ubiquitination Protein K11-linked Ubiquitination Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cell Cycle Process ISG15-protein Conjugation Catabolic Process Cellular Protein Metabolic Process Cellular Protein Modification Process Toll-like Receptor 4 Signaling Pathway Protein Monoubiquitination Cell Cycle Toll-like Receptor Signaling Pathway Mitotic Cell Cycle Process Pattern Recognition Receptor Signaling Pathway Mitotic Cell Cycle Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Activation Of Innate Immune Response Cellular Response To Organic Substance Response To Organic Substance Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Metabolic Process Positive Regulation Of Innate Immune Response Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Stimulus Response To Stimulus Regulation Of Chromosome Organization Regulation Of Protein Ubiquitination Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Proteolysis Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Mitotic Spindle Assembly Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Immune Response Regulation Of Cell Cycle Phase Transition
Tagcloud ?		ablates associates dimethyl drosophila ectopic eggs establishment exhibits finger gametogenesis germ germline h3k4me2 homologs identity male phd preference reader rescues sexual soma sperm spermatogenesis spermatogonia strikingly tails testis xx	aldo1 anxa2 cdna cerebral characterize coding cortical ddit3 egr1 endoplasmic ero1l fold gadd153 gas5 giig11 gpi1 hig1 hypoxia microarray ndr1 neuronal p4hb profiling reinforce repressed reticulum sac1p ubiquitination vdac2
Tagcloud (Difference) ?		ablates associates dimethyl drosophila ectopic eggs establishment exhibits finger gametogenesis germ germline h3k4me2 homologs identity male phd preference reader rescues sexual soma sperm spermatogenesis spermatogonia strikingly tails testis xx	aldo1 anxa2 cdna cerebral characterize coding cortical ddit3 egr1 endoplasmic ero1l fold gadd153 gas5 giig11 gpi1 hig1 hypoxia microarray ndr1 neuronal p4hb profiling reinforce repressed reticulum sac1p ubiquitination vdac2
Tagcloud (Intersection) ?