PHF7 and MAGEF1

Number of citations of the paper that reports this interaction (PubMedID 25590999)
60

Data Source:
BioGRID (two hybrid)

		PHF7	MAGEF1
Description		PHD finger protein 7	MAGE family member F1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus Cytosol Plasma Membrane Nuclear Speck	Nucleus
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Osteoclast Proliferation	Negative Regulation Of Transcription By RNA Polymerase II Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Parkinson's disease ( 28892059) Schizophrenia ( 23974872) Triglyceride levels ( 32154731)	Cerebral amyloid deposition (PET imaging) ( 30361487) Nose size ( 27182965)
Interacting Genes		18 interacting genes: APP ARIH2 DTX3L FBXL17 H3-4 IKBKG MAGEF1 MDM2 RNF111 RNF14 RNF34 SRPK1 TRIM26 TRIM41 UBE2D2 UBE2D4 USP1 USP15	6 interacting genes: MDFI MMS19 NSMCE1 PHF7 TRAIP TRIM27
Entrez ID		51533	64110
HPRD ID		15127	14348
Ensembl ID		ENSG00000010318	ENSG00000177383
Uniprot IDs		A0A024R336 A8K856 Q9BWX1	Q9HAY2
PDB IDs
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification Protein Ubiquitination Protein Polyubiquitination Protein Modification Process Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Proteolysis Involved In Protein Catabolic Process Ubiquitin Protein Ligase Activity Protein Metabolic Process Macromolecule Catabolic Process Nucleus Protein K48-linked Ubiquitination Macromolecule Metabolic Process Ubiquitin-protein Transferase Activity Transferase Activity Catabolic Process Nucleoplasm Innate Immune Response Defense Response To Symbiont Defense Response To Other Organism Regulation Of Cellular Response To Stress Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Monoubiquitinated Protein Deubiquitination Response To Virus Regulation Of Signal Transduction Protein Autoubiquitination Zinc Ion Binding Response To Stress Response To Other Organism Protein-containing Complex Proteasomal Protein Catabolic Process Immune Response Regulation Of Cell Communication Regulation Of Signaling Defense Response To Virus Ubiquitin Ligase Complex Response To External Biotic Stimulus Intracellular Signal Transduction Regulation Of Signal Transduction By P53 Class Mediator Defense Response Immune System Process Protein K6-linked Ubiquitination Protein Catabolic Process Amyloid Fibril Formation Cytosol Ubiquitin Conjugating Enzyme Binding	Ubiquitin Protein Ligase Activity Protein Sumoylation Ubiquitin-protein Transferase Activity Negative Regulation Of Type I Interferon Production DNA Repair Post-translational Protein Modification Zinc Ion Binding Regulation Of Type I Interferon Production Transferase Activity Protein Modification By Small Protein Conjugation DNA Metabolic Process DNA Damage Response Negative Regulation Of Osteoclast Proliferation Cytosolic [4Fe-4S] Assembly Targeting Complex MMXD Complex Phosphatidylinositol 3-kinase Inhibitor Activity Nucleus Protein-DNA Covalent Cross-linking Repair Nucleoplasm Smc5-Smc6 Complex Transcription Coactivator Activity Positive Regulation Of Actin Nucleation Transcription Factor TFIIH Holo Complex Dorsal/ventral Axis Specification Trophoblast Giant Cell Differentiation Negative Regulation Of Cytokine Production Negative Regulation Of Viral Transcription Negative Regulation Of Interferon-beta Production Chromatin Looping Suppression Of Viral Release By Host Arp2/3 Complex-mediated Actin Nucleation Regulation Of Viral Transcription SUMO Transferase Activity Retromer Complex
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