PHF7 and RNF14

Number of citations of the paper that reports this interaction (PubMedID 22493164)
44

Data Source:
BioGRID (two hybrid)

		PHF7	RNF14
Description		PHD finger protein 7	ring finger protein 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus Cytosol Plasma Membrane Nuclear Speck	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Cytosolic Ribosome
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Nuclear Androgen Receptor Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Osteoclast Proliferation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Translational Elongation Translational Termination Ubiquitin-dependent Protein Catabolic Process Signal Transduction Protein Ubiquitination Androgen Receptor Signaling Pathway Positive Regulation Of DNA-templated Transcription Regulation Of Androgen Receptor Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Rescue Of Stalled Ribosome Protein K6-linked Ubiquitination Protein-RNA Covalent Cross-linking Repair
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Parkinson's disease ( 28892059) Schizophrenia ( 23974872) Triglyceride levels ( 32154731)	Asthma ( 31959851) Superior temporal gyrus volume ( 31530798)
Interacting Genes		18 interacting genes: APP ARIH2 DTX3L FBXL17 H3-4 IKBKG MAGEF1 MDM2 RNF111 RNF14 RNF34 SRPK1 TRIM26 TRIM41 UBE2D2 UBE2D4 USP1 USP15	23 interacting genes: AR DACH1 ESR1 HNF1A HNRNPA1 NCOA4 NR3C1 PHF7 TAGLN TENT5A TNFAIP3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2L3 UBE2U UBE2V1 UBE2W VDR
Entrez ID		51533	9604
HPRD ID		15127	05745
Ensembl ID		ENSG00000010318	ENSG00000013561
Uniprot IDs		A0A024R336 A8K856 Q9BWX1	B7Z229 Q9UBS8
PDB IDs
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification Protein Ubiquitination Protein Polyubiquitination Protein Modification Process Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Proteolysis Involved In Protein Catabolic Process Ubiquitin Protein Ligase Activity Protein Metabolic Process Macromolecule Catabolic Process Nucleus Protein K48-linked Ubiquitination Macromolecule Metabolic Process Ubiquitin-protein Transferase Activity Transferase Activity Catabolic Process Nucleoplasm Innate Immune Response Defense Response To Symbiont Defense Response To Other Organism Regulation Of Cellular Response To Stress Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Monoubiquitinated Protein Deubiquitination Response To Virus Regulation Of Signal Transduction Protein Autoubiquitination Zinc Ion Binding Response To Stress Response To Other Organism Protein-containing Complex Proteasomal Protein Catabolic Process Immune Response Regulation Of Cell Communication Regulation Of Signaling Defense Response To Virus Ubiquitin Ligase Complex Response To External Biotic Stimulus Intracellular Signal Transduction Regulation Of Signal Transduction By P53 Class Mediator Defense Response Immune System Process Protein K6-linked Ubiquitination Protein Catabolic Process Amyloid Fibril Formation Cytosol Ubiquitin Conjugating Enzyme Binding	Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Ubiquitin-protein Transferase Activity Protein K48-linked Ubiquitination Protein Ubiquitination Protein K11-linked Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Monoubiquitination Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Transferase Activity Nuclear Receptor-mediated Signaling Pathway Estrogen Response Element Binding Protein Modification Process Intracellular Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Nuclear Receptor Activity Cellular Response To Estrogen Stimulus Hormone-mediated Signaling Pathway Proteolysis Involved In Protein Catabolic Process Protein K63-linked Ubiquitination Nuclear Steroid Receptor Activity Estrogen Receptor Signaling Pathway Nucleus Negative Regulation Of Osteoclast Proliferation Nucleoplasm Steroid Binding ATP Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Mammary Gland Branching Involved In Pregnancy ISG15 Transferase Activity Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Proteolysis Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Positive Regulation Of Bone Mineralization ISG15-protein Conjugation Cellular Response To Lipid Cellular Response To Testosterone Stimulus Regulation Of RNA Metabolic Process Positive Regulation Of Biomineral Tissue Development Nucleotide Binding Macromolecule Catabolic Process Positive Regulation Of Ossification Protein-containing Complex
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