VPS51 and YTHDC1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		VPS51	YTHDC1
Gene Name		vacuolar protein sorting 51 homolog (S. cerevisiae)	YTH domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	GARP Complex Golgi Apparatus Integral Component Of Membrane	Nucleus Nuclear Body
	Molecular Function	Molecular_function Protein Binding	RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Lipid Transport Autophagy Protein Transport Retrograde Transport, Endosome To Golgi	MRNA Splice Site Selection
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		7 interactors: CDKN1A GSK3B NUDT3 VPS52 VPS53 VPS54 YTHDC1	34 interactors: ABL1 ADAMTS4 CFH CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 LAMC3 LAMTOR5 LZTS2 MPRIP PLG PROSER2 RBMY1F SDCBP2 SEPT10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51
Entrez ID		738	91746
HPRD ID		12605	11689
Ensembl ID		ENSG00000149823	ENSG00000083896
Uniprot IDs		Q9UID3	J3QR07 Q96MU7
PDB IDs			2YUD
Enriched GO Terms of Interacting Partners?		Cellular Response To Heat Retrograde Transport, Endosome To Golgi Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Protein Transport Establishment Of Protein Localization Response To Heat Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Protein Serine/threonine Kinase Activity Phosphatidylinositol-mediated Signaling Digestive Tract Development Digestive System Development Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Protein Import Into Nucleus Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Protein Localization Cellular Response To Fibroblast Growth Factor Stimulus Response To Temperature Stimulus Response To Fibroblast Growth Factor Cellular Response To Interleukin-3 Intestinal Epithelial Cell Maturation Regulation Of Protein Localization To Nucleus Endosomal Transport Regulation Of Nucleocytoplasmic Transport Neurotrophin TRK Receptor Signaling Pathway Ectodermal Cell Differentiation Negative Regulation Of Protein Kinase Activity Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Regulation Of Neuron Maturation Negative Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Kinase Activity Cellular Response To UV-B Golgi To Vacuole Transport Protein Localization To Microtubule Negative Regulation Of Dendrite Morphogenesis Regulation Of Intracellular Protein Transport Fc Receptor Signaling Pathway Negative Regulation Of NFAT Protein Import Into Nucleus ER Overload Response Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glycogen Biosynthetic Process Stress-induced Premature Senescence	MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Peptidyl-tyrosine Autophosphorylation Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Protein Autophosphorylation Regulation Of Cell-cell Adhesion RNA Metabolic Process Peptidyl-tyrosine Phosphorylation Regulation Of Wnt Signaling Pathway Gene Expression Viral Process Innate Immune Response Regulation Of Cell Proliferation Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Regulation Of Cell Adhesion Anatomical Structure Development Leukocyte Migration Regulation Of Canonical Wnt Signaling Pathway Immune Response Regulation Of RNA Metabolic Process Regulation Of Intracellular Transport Cytoplasmic Transport Defense Response Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Localization Activated T Cell Proliferation Phagocytosis Positive Regulation Of Viral Genome Replication Regulation Of Neuron Death Heterocycle Metabolic Process Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Aromatic Compound Metabolic Process Nuclear Export Regulation Of T Cell Activation Nucleus Organization Regulation Of Gene Expression Developmental Process Regulation Of Nitrogen Compound Metabolic Process Antigen Receptor-mediated Signaling Pathway Cellular Nitrogen Compound Metabolic Process Cellular Process Golgi To Plasma Membrane Transport
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