VPS51

Description		VPS51 subunit of GARP complex
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GO Annotations	Cellular Component	GARP Complex Nucleolus Endosome Golgi Apparatus Trans-Golgi Network Cytosol Membrane Trans-Golgi Network Membrane Recycling Endosome EARP Complex
	Molecular Function	Protein Binding
	Biological Process	Protein Targeting Lipid Transport Autophagy Golgi Organization Lysosomal Transport Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Brain Morphogenesis Vesicle-mediated Cholesterol Transport
Pathways		Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Serum uric acid levels ( 32514006)
Interacting Genes		6 interacting genes: CDKN1A FXR1 GSK3B NUDT3 VPS54 YTHDC1
Entrez ID		738
HPRD ID		12605
Ensembl ID		ENSG00000149823
Uniprot IDs		Q9UID3
PDB IDs		4J2C
Enriched GO Terms of Interacting Partners?		Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Chordate Embryonic Development In Utero Embryonic Development Presynaptic Modulation Of Chemical Synaptic Transmission Cytoplasmic Translational Initiation Regulation Of Long-term Synaptic Potentiation Tissue Regeneration PCNA-p21 Complex Cell Cycle G1/S Phase Transition Cellular Localization Negative Regulation Of Cardiac Muscle Tissue Regeneration Regulation Of Growth G1/S Transition Of Mitotic Cell Cycle Regeneration Negative Regulation Of Gene Expression Negative Regulation Of Protein Metabolic Process Regulation Of Circadian Rhythm Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Microtubule Anchoring At Centrosome Glutamatergic Synapse Translational Initiation Regulation Of Translation At Presynapse, Modulating Synaptic Transmission MRNA Transport 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Diphosphoinositol Polyphosphate Metabolic Process Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Diphosphoinositol Polyphosphate Catabolic Process Bis(5'-adenosyl)-hexaphosphatase Activity Diadenosine Hexaphosphate Catabolic Process Inositol Phosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process Diphosphoinositol-polyphosphate Diphosphatase Activity Endopolyphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Neural Tissue Regeneration Post-embryonic Forelimb Morphogenesis Primary Follicle Stage Mammalian Oogenesis Stage Mitotic Cell Cycle Phase Transition RNA Transport Negative Regulation Of Catalytic Activity Cell Cycle Phase Transition
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