UBE2V2 and SHPRH

Number of citations of the paper that reports this interaction (PMID 17108083)
51

Data Source:
BioGRID (pull down)

		UBE2V2	SHPRH
Gene Name		ubiquitin-conjugating enzyme E2 variant 2	SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm UBC13-MMS2 Complex Extracellular Vesicular Exosome	Nucleosome Nucleus
	Molecular Function	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity	DNA Binding Helicase Activity Ubiquitin-protein Transferase Activity ATP Binding Zinc Ion Binding Ligase Activity
	Biological Process	Protein Polyubiquitination DNA Double-strand Break Processing Regulation Of DNA Repair Postreplication Repair Cell Proliferation Positive Regulation Of Neuron Projection Development Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of DNA Repair Positive Regulation Of Synapse Assembly Protein K63-linked Ubiquitination	Protein Polyubiquitination DNA Repair Nucleosome Assembly
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: BCL10 DZIP3 EGFR HLTF IGSF21 LRIF1 MALT1 MKRN3 MOB4 OTUB1 RNF144A RNF2 RNF8 SHPRH SIAH1 SUV39H2 TRAF2 TRIM5 UBC UBE2N XIAP ZNRF1	10 interactors: C17orf59 EDARADD FBXW7 FDFT1 LPP PCNA RAD18 UBE2N UBE2V2 YWHAG
Entrez ID		7336	257218
HPRD ID		04300	10476
Ensembl ID			ENSG00000146414
Uniprot IDs		A0M8W4 G3V113 Q15819	B3KX98 K4DI94 Q149N8
PDB IDs		1J74 1J7D 1ZGU 3VON 4EPO	2M85
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Cellular Protein Modification Process Cellular Protein Metabolic Process Protein Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Protein Ubiquitination Protein K63-linked Ubiquitination Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Innate Immune Response Immune Response-regulating Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Activation Of Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of DNA Repair Regulation Of Immune Response Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Innate Immune Response Positive Regulation Of Signal Transduction Response To Stress Fc-epsilon Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Stress Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Fc Receptor Signaling Pathway Innate Immune Response Histone Ubiquitination Regulation Of Histone Ubiquitination Positive Regulation Of DNA Repair Regulation Of Response To DNA Damage Stimulus Cellular Response To DNA Damage Stimulus Antigen Receptor-mediated Signaling Pathway Cellular Metabolic Process Immune Response Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Modification Process Regulation Of Immune System Process DNA Repair Protein Catabolic Process Positive Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Chromatin Organization Positive Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Cellular Protein Metabolic Process	Postreplication Repair DNA Double-strand Break Processing Cellular Response To DNA Damage Stimulus Positive Regulation Of DNA Metabolic Process Protein Ubiquitination DNA Repair Protein Modification By Small Protein Conjugation Protein K63-linked Ubiquitination DNA Catabolic Process, Exonucleolytic Positive Regulation Of DNA Repair Cellular Response To Stress Regulation Of DNA Repair Positive Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Deoxyribonuclease Activity Negative Regulation Of SREBP Signaling Pathway DNA Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of DNA Metabolic Process Negative Regulation Of Triglyceride Biosynthetic Process Leading Strand Elongation Regulation Of Response To DNA Damage Stimulus Regulation Of DNA Replication Response To UV Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Farnesyl Diphosphate Metabolic Process Positive Regulation Of Protein Ubiquitination DNA Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Double-strand Break Repair Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Histone Ubiquitination Negative Regulation Of Hepatocyte Proliferation Trachea Gland Development Protein Polyubiquitination Negative Regulation Of DNA Endoreduplication Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Cellular Response To Stimulus Positive Regulation Of Oxidative Stress-induced Cell Death Positive Regulation Of Protein Catabolic Process Cellular Macromolecule Catabolic Process DNA Recombination Regulation Of Neuron Apoptotic Process Regulation Of DNA Endoreduplication Mitotic Cell Cycle Phase Transition
Tagcloud ?		affymetrix anthracycline anthracyclines atm bc bimodal bub1 damaging enable fan1 fanci fashion impair mnat1 msh2 msh6 mtmr15 parp2 pcna pms2 polq recql4 regimens residual rpa3 sensitizing survive taxane top2a
Tagcloud (Difference) ?		affymetrix anthracycline anthracyclines atm bc bimodal bub1 damaging enable fan1 fanci fashion impair mnat1 msh2 msh6 mtmr15 parp2 pcna pms2 polq recql4 regimens residual rpa3 sensitizing survive taxane top2a
Tagcloud (Intersection) ?