SHPRH

Gene Name		SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
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Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus
	Molecular Function	DNA Binding Helicase Activity Ubiquitin-protein Transferase Activity ATP Binding Zinc Ion Binding Ligase Activity
	Biological Process	Protein Polyubiquitination DNA Repair Nucleosome Assembly
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: C17orf59 EDARADD FBXW7 FDFT1 LPP PCNA RAD18 UBE2N UBE2V2 YWHAG
Entrez ID		257218
HPRD ID		10476
Ensembl ID		ENSG00000146414
Uniprot IDs		B3KX98 K4DI94 Q149N8
PDB IDs		2M85
Enriched GO Terms of Interacting Partners?		Postreplication Repair DNA Double-strand Break Processing Cellular Response To DNA Damage Stimulus Positive Regulation Of DNA Metabolic Process Protein Ubiquitination DNA Repair Protein Modification By Small Protein Conjugation Protein K63-linked Ubiquitination DNA Catabolic Process, Exonucleolytic Positive Regulation Of DNA Repair Cellular Response To Stress Regulation Of DNA Repair Positive Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Deoxyribonuclease Activity Negative Regulation Of SREBP Signaling Pathway DNA Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of DNA Metabolic Process Negative Regulation Of Triglyceride Biosynthetic Process Leading Strand Elongation Regulation Of Response To DNA Damage Stimulus Regulation Of DNA Replication Response To UV Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Farnesyl Diphosphate Metabolic Process Positive Regulation Of Protein Ubiquitination DNA Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Double-strand Break Repair Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Histone Ubiquitination Negative Regulation Of Hepatocyte Proliferation Trachea Gland Development Protein Polyubiquitination Negative Regulation Of DNA Endoreduplication Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Cellular Response To Stimulus Positive Regulation Of Oxidative Stress-induced Cell Death Positive Regulation Of Protein Catabolic Process Cellular Macromolecule Catabolic Process DNA Recombination Regulation Of Neuron Apoptotic Process Regulation Of DNA Endoreduplication Mitotic Cell Cycle Phase Transition
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