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SHPRH and UBE2V2
Number of citations of the paper that reports this interaction (PMID
17108083
)
51
Data Source:
BioGRID
(pull down)
SHPRH
UBE2V2
Gene Name
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
ubiquitin-conjugating enzyme E2 variant 2
Image
Gene Ontology Annotations
Cellular Component
Nucleosome
Nucleus
Nucleus
Cytoplasm
UBC13-MMS2 Complex
Extracellular Vesicular Exosome
Molecular Function
DNA Binding
Helicase Activity
Ubiquitin-protein Transferase Activity
ATP Binding
Zinc Ion Binding
Ligase Activity
Protein Binding
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Biological Process
Protein Polyubiquitination
DNA Repair
Nucleosome Assembly
Protein Polyubiquitination
DNA Double-strand Break Processing
Regulation Of DNA Repair
Postreplication Repair
Cell Proliferation
Positive Regulation Of Neuron Projection Development
Protein Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of DNA Repair
Positive Regulation Of Synapse Assembly
Protein K63-linked Ubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
C17orf59
EDARADD
FBXW7
FDFT1
LPP
PCNA
RAD18
UBE2N
UBE2V2
YWHAG
22 interactors:
BCL10
DZIP3
EGFR
HLTF
IGSF21
LRIF1
MALT1
MKRN3
MOB4
OTUB1
RNF144A
RNF2
RNF8
SHPRH
SIAH1
SUV39H2
TRAF2
TRIM5
UBC
UBE2N
XIAP
ZNRF1
Entrez ID
257218
7336
HPRD ID
10476
04300
Ensembl ID
ENSG00000146414
Uniprot IDs
B3KX98
K4DI94
Q149N8
A0M8W4
G3V113
Q15819
PDB IDs
2M85
1J74
1J7D
1ZGU
3VON
4EPO
Enriched GO Terms of Interacting Partners
?
Postreplication Repair
DNA Double-strand Break Processing
Cellular Response To DNA Damage Stimulus
Positive Regulation Of DNA Metabolic Process
Protein Ubiquitination
DNA Repair
Protein Modification By Small Protein Conjugation
Protein K63-linked Ubiquitination
DNA Catabolic Process, Exonucleolytic
Positive Regulation Of DNA Repair
Cellular Response To Stress
Regulation Of DNA Repair
Positive Regulation Of Response To DNA Damage Stimulus
Positive Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Deoxyribonuclease Activity
Negative Regulation Of SREBP Signaling Pathway
DNA Metabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of DNA Metabolic Process
Negative Regulation Of Triglyceride Biosynthetic Process
Leading Strand Elongation
Regulation Of Response To DNA Damage Stimulus
Regulation Of DNA Replication
Response To UV
Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Farnesyl Diphosphate Metabolic Process
Positive Regulation Of Protein Ubiquitination
DNA Catabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Double-strand Break Repair
Positive Regulation Of Cellular Protein Catabolic Process
Regulation Of Histone Ubiquitination
Negative Regulation Of Hepatocyte Proliferation
Trachea Gland Development
Protein Polyubiquitination
Negative Regulation Of DNA Endoreduplication
Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Protein Ubiquitination
Cellular Response To Stimulus
Positive Regulation Of Oxidative Stress-induced Cell Death
Positive Regulation Of Protein Catabolic Process
Cellular Macromolecule Catabolic Process
DNA Recombination
Regulation Of Neuron Apoptotic Process
Regulation Of DNA Endoreduplication
Mitotic Cell Cycle Phase Transition
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Protein Ubiquitination
Protein K63-linked Ubiquitination
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Innate Immune Response
Immune Response-regulating Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Protein Ubiquitination
Activation Of Innate Immune Response
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of DNA Repair
Regulation Of Immune Response
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Innate Immune Response
Positive Regulation Of Signal Transduction
Response To Stress
Fc-epsilon Receptor Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Response To Stress
Toll-like Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Fc Receptor Signaling Pathway
Innate Immune Response
Histone Ubiquitination
Regulation Of Histone Ubiquitination
Positive Regulation Of DNA Repair
Regulation Of Response To DNA Damage Stimulus
Cellular Response To DNA Damage Stimulus
Antigen Receptor-mediated Signaling Pathway
Cellular Metabolic Process
Immune Response
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Protein Modification Process
Regulation Of Immune System Process
DNA Repair
Protein Catabolic Process
Positive Regulation Of Cytokine Production Involved In Immune Response
Positive Regulation Of Immune Response
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Chromatin Organization
Positive Regulation Of Response To DNA Damage Stimulus
Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud
?
affymetrix
anthracycline
anthracyclines
atm
bc
bimodal
bub1
damaging
enable
fan1
fanci
fashion
impair
mnat1
msh2
msh6
mtmr15
parp2
pcna
pms2
polq
recql4
regimens
residual
rpa3
sensitizing
survive
taxane
top2a
Tagcloud (Difference)
?
affymetrix
anthracycline
anthracyclines
atm
bc
bimodal
bub1
damaging
enable
fan1
fanci
fashion
impair
mnat1
msh2
msh6
mtmr15
parp2
pcna
pms2
polq
recql4
regimens
residual
rpa3
sensitizing
survive
taxane
top2a
Tagcloud (Intersection)
?