SHPRH and C17orf59

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SHPRH	C17orf59
Gene Name		SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase	chromosome 17 open reading frame 59
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus
	Molecular Function	DNA Binding Helicase Activity Ubiquitin-protein Transferase Activity ATP Binding Zinc Ion Binding Ligase Activity
	Biological Process	Protein Polyubiquitination DNA Repair Nucleosome Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: C17orf59 EDARADD FBXW7 FDFT1 LPP PCNA RAD18 UBE2N UBE2V2 YWHAG	5 interactors: EPS8 FBXO44 MOS PLA2G4A SHPRH
Entrez ID		257218	54785
HPRD ID		10476	13368
Ensembl ID		ENSG00000146414	ENSG00000196544
Uniprot IDs		B3KX98 K4DI94 Q149N8	Q96GS4
PDB IDs		2M85
Enriched GO Terms of Interacting Partners?		Postreplication Repair DNA Double-strand Break Processing Cellular Response To DNA Damage Stimulus Positive Regulation Of DNA Metabolic Process Protein Ubiquitination DNA Repair Protein Modification By Small Protein Conjugation Protein K63-linked Ubiquitination DNA Catabolic Process, Exonucleolytic Positive Regulation Of DNA Repair Cellular Response To Stress Regulation Of DNA Repair Positive Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Deoxyribonuclease Activity Negative Regulation Of SREBP Signaling Pathway DNA Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of DNA Metabolic Process Negative Regulation Of Triglyceride Biosynthetic Process Leading Strand Elongation Regulation Of Response To DNA Damage Stimulus Regulation Of DNA Replication Response To UV Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Farnesyl Diphosphate Metabolic Process Positive Regulation Of Protein Ubiquitination DNA Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Double-strand Break Repair Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Histone Ubiquitination Negative Regulation Of Hepatocyte Proliferation Trachea Gland Development Protein Polyubiquitination Negative Regulation Of DNA Endoreduplication Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Cellular Response To Stimulus Positive Regulation Of Oxidative Stress-induced Cell Death Positive Regulation Of Protein Catabolic Process Cellular Macromolecule Catabolic Process DNA Recombination Regulation Of Neuron Apoptotic Process Regulation Of DNA Endoreduplication Mitotic Cell Cycle Phase Transition	Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle Actin Polymerization-dependent Cell Motility Negative Regulation Of Meiotic Cell Cycle Phase Transition Platelet Activating Factor Biosynthetic Process Platelet Activating Factor Metabolic Process Establishment Of Meiotic Spindle Localization Exit From Mitosis Cardiolipin Acyl-chain Remodeling Behavioral Response To Ethanol Cardiolipin Metabolic Process Meiotic Spindle Organization Arachidonic Acid Secretion Phosphatidylinositol Acyl-chain Remodeling Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Rac Protein Signal Transduction Phosphatidylethanolamine Acyl-chain Remodeling Cellular Response To Antibiotic Barbed-end Actin Filament Capping Actin Crosslink Formation Dendritic Cell Migration Phosphatidylcholine Acyl-chain Remodeling Cellular Response To Toxic Substance Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Phospholipid Catabolic Process Phosphatidylserine Metabolic Process Negative Regulation Of Meiotic Cell Cycle Chromatin Organization Cellular Response To Stimulus Long-chain Fatty Acid Transport Regulation Of Meiosis Establishment Of Spindle Orientation Actin Filament Capping Icosanoid Biosynthetic Process Regulation Of Organelle Organization Organelle Organization Regulation Of Meiotic Cell Cycle Spindle Localization Phosphatidylcholine Metabolic Process Negative Regulation Of Actin Filament Depolymerization Response To Antibiotic Acid Secretion Fatty Acid Transport Chromosome Organization Actin Cytoskeleton Reorganization Cell Cycle Process Actin Filament Bundle Assembly Arachidonic Acid Metabolic Process
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