SHPRH and LPP

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		SHPRH	LPP
Gene Name		SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase	LIM domain containing preferred translocation partner in lipoma
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus	Nucleus Cytoplasm Plasma Membrane Focal Adhesion
	Molecular Function	DNA Binding Helicase Activity Ubiquitin-protein Transferase Activity ATP Binding Zinc Ion Binding Ligase Activity	Protein Binding Zinc Ion Binding
	Biological Process	Protein Polyubiquitination DNA Repair Nucleosome Assembly	Cell Adhesion Biological_process
Pathways
Drugs
Diseases
GWAS			B cell non-Hodgkin lymphoma ( 23749188) Celiac disease ( 20190752 18311140) IgE levels ( 22075330) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Obesity-related traits ( 23251661) Renal function-related traits (BUN) ( 22797727) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Vitiligo ( 22951725 20410501) White matter integrity (interaction) ( 23218918)
Protein-Protein Interactions		10 interactors: C17orf59 EDARADD FBXW7 FDFT1 LPP PCNA RAD18 UBE2N UBE2V2 YWHAG	6 interactors: ACTN1 ATP5J2 ATRAID SCRIB SHPRH VASP
Entrez ID		257218	4026
HPRD ID		10476	02828
Ensembl ID		ENSG00000146414	ENSG00000145012
Uniprot IDs		B3KX98 K4DI94 Q149N8	B7Z8W0 B7ZLW0 Q93052
PDB IDs		2M85
Enriched GO Terms of Interacting Partners?		Postreplication Repair DNA Double-strand Break Processing Cellular Response To DNA Damage Stimulus Positive Regulation Of DNA Metabolic Process Protein Ubiquitination DNA Repair Protein Modification By Small Protein Conjugation Protein K63-linked Ubiquitination DNA Catabolic Process, Exonucleolytic Positive Regulation Of DNA Repair Cellular Response To Stress Regulation Of DNA Repair Positive Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Deoxyribonuclease Activity Negative Regulation Of SREBP Signaling Pathway DNA Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of DNA Metabolic Process Negative Regulation Of Triglyceride Biosynthetic Process Leading Strand Elongation Regulation Of Response To DNA Damage Stimulus Regulation Of DNA Replication Response To UV Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Farnesyl Diphosphate Metabolic Process Positive Regulation Of Protein Ubiquitination DNA Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Double-strand Break Repair Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Histone Ubiquitination Negative Regulation Of Hepatocyte Proliferation Trachea Gland Development Protein Polyubiquitination Negative Regulation Of DNA Endoreduplication Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Cellular Response To Stimulus Positive Regulation Of Oxidative Stress-induced Cell Death Positive Regulation Of Protein Catabolic Process Cellular Macromolecule Catabolic Process DNA Recombination Regulation Of Neuron Apoptotic Process Regulation Of DNA Endoreduplication Mitotic Cell Cycle Phase Transition	Protein Localization To Cell Junction Neural Tube Closure Neural Tube Formation Embryonic Epithelial Tube Formation Epithelial Tube Formation Negative Regulation Of Cyclin Catabolic Process Tube Formation Morphogenesis Of Embryonic Epithelium Protein Localization To Tight Junction Cochlear Nucleus Development Protein Localization To Adherens Junction Neural Tube Development Cell Junction Assembly Establishment Of Apical/basal Cell Polarity Synaptic Vesicle Targeting Astrocyte Cell Migration Actin Filament Organization Auditory Receptor Cell Stereocilium Organization Establishment Of Monopolar Cell Polarity Exocytosis Pons Development Negative Regulation Of Osteoblast Proliferation Auditory Receptor Cell Morphogenesis Activation Of Rac GTPase Activity Epithelial Tube Morphogenesis Mitochondrial ATP Synthesis Coupled Proton Transport Auditory Receptor Cell Development Actin Crosslink Formation Positive Regulation Of Receptor Recycling Tube Morphogenesis Inner Ear Receptor Stereocilium Organization
Tagcloud ?			arousal behavioural correlation degree denenberg describes direction documented exhibit lateral lateralities medial mpp paw periods preference preferences regardless relations rodents seemingly side sp spatial states strength strong terms waters
Tagcloud (Difference) ?			arousal behavioural correlation degree denenberg describes direction documented exhibit lateral lateralities medial mpp paw periods preference preferences regardless relations rodents seemingly side sp spatial states strength strong terms waters
Tagcloud (Intersection) ?