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SEMA3F and NRP1
Number of citations of the paper that reports this interaction (PubMedID
9883722
)
0
Data Source:
HPRD
(in vivo, in vitro)
SEMA3F
NRP1
Description
semaphorin 3F
neuropilin 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Plasma Membrane
Glutamatergic Synapse
Semaphorin Receptor Complex
Extracellular Region
Extracellular Space
Cytoplasm
Mitochondrion
Early Endosome
Cytosol
Neurofilament
Plasma Membrane
Focal Adhesion
Membrane
Axon
Cytoplasmic Vesicle
Mitochondrial Membrane
Neuron Projection
Receptor Complex
Postsynaptic Membrane
Sorting Endosome
Glutamatergic Synapse
Molecular Function
Signaling Receptor Binding
Semaphorin Receptor Binding
Neuropilin Binding
Chemorepellent Activity
Vascular Endothelial Growth Factor Receptor Activity
GTPase Activator Activity
Protein Binding
Heparin Binding
Coreceptor Activity
Semaphorin Receptor Activity
Growth Factor Binding
Protein Kinase Binding
Cytokine Binding
Vascular Endothelial Growth Factor Binding
Metal Ion Binding
Biological Process
Neural Crest Cell Migration
Signal Transduction
Axon Guidance
Facial Nerve Structural Organization
Trigeminal Nerve Structural Organization
Nerve Development
Branchiomotor Neuron Axon Guidance
Positive Regulation Of Cell Migration
Trunk Neural Crest Cell Migration
Ventral Trunk Neural Crest Cell Migration
System Development
Negative Regulation Of Axon Extension Involved In Axon Guidance
Axon Extension Involved In Axon Guidance
Negative Chemotaxis
Sympathetic Ganglion Development
Semaphorin-plexin Signaling Pathway
Sympathetic Neuron Projection Extension
Sympathetic Neuron Projection Guidance
Regulation Of Postsynapse Organization
Neural Crest Cell Migration Involved In Autonomic Nervous System Development
Angiogenesis
Branching Involved In Blood Vessel Morphogenesis
Vasculogenesis
Neural Crest Cell Migration
Neuron Migration
Positive Regulation Of Endothelial Cell Proliferation
Sprouting Angiogenesis
Cell Migration Involved In Sprouting Angiogenesis
Outflow Tract Septum Morphogenesis
Substrate-dependent Cell Migration, Cell Extension
Signal Transduction
Integrin-mediated Signaling Pathway
Cell-cell Signaling
Nervous System Development
Axon Guidance
Axonal Fasciculation
Heart Development
Motor Neuron Axon Guidance
Response To Wounding
Animal Organ Morphogenesis
Positive Regulation Of Endothelial Cell Migration
Positive Regulation Of Smooth Muscle Cell Migration
Dendrite Development
Facial Nerve Structural Organization
Trigeminal Nerve Morphogenesis
Trigeminal Nerve Structural Organization
Vestibulocochlear Nerve Structural Organization
Branchiomotor Neuron Axon Guidance
Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus
Cell Differentiation
Negative Regulation Of Axon Extension
Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Retinal Ganglion Cell Axon Guidance
Regulation Of Cdc42 Protein Signal Transduction
Cellular Response To Hepatocyte Growth Factor Stimulus
Endothelial Cell Chemotaxis
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Ventral Trunk Neural Crest Cell Migration
Vascular Endothelial Growth Factor Signaling Pathway
Neuropilin Signaling Pathway
VEGF-activated Neuropilin Signaling Pathway
Positive Regulation Of Phosphorylation
Negative Regulation Of Neuron Apoptotic Process
Blood Vessel Endothelial Cell Migration
Endothelial Cell Migration
Positive Regulation Of Angiogenesis
Symbiont Entry Into Host Cell
Platelet-derived Growth Factor Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Hepatocyte Growth Factor Receptor Signaling Pathway
Sympathetic Nervous System Development
Neuron Development
Axon Extension
Regulation Of Axon Extension Involved In Axon Guidance
Positive Regulation Of Axon Extension Involved In Axon Guidance
Negative Regulation Of Axon Extension Involved In Axon Guidance
Artery Morphogenesis
Axon Extension Involved In Axon Guidance
Positive Chemotaxis
Positive Regulation Of Filopodium Assembly
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Focal Adhesion Assembly
Axonogenesis Involved In Innervation
Regulation Of Vesicle-mediated Transport
Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching
Angiogenesis Involved In Coronary Vascular Morphogenesis
Coronary Artery Morphogenesis
Retina Vasculature Development In Camera-type Eye
Retina Vasculature Morphogenesis In Camera-type Eye
Renal Artery Morphogenesis
Sympathetic Ganglion Development
Trigeminal Ganglion Development
Positive Regulation Of ERK1 And ERK2 Cascade
Semaphorin-plexin Signaling Pathway
Commissural Neuron Axon Guidance
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Endothelial Tip Cell Fate Specification
Sensory Neuron Axon Guidance
Motor Neuron Migration
Sympathetic Neuron Projection Extension
Sympathetic Neuron Projection Guidance
Postsynapse Organization
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Basal Dendrite Development
Basal Dendrite Arborization
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Neural Crest Cell Migration Involved In Autonomic Nervous System Development
Protein Localization To Early Endosome
Facioacoustic Ganglion Development
Dorsal Root Ganglion Morphogenesis
Otic Placode Development
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Neurophilin interactions with VEGF and VEGFR
Signaling by ROBO receptors
Sema3A PAK dependent Axon repulsion
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
CRMPs in Sema3A signaling
CRMPs in Sema3A signaling
Signal transduction by L1
CHL1 interactions
Attachment and Entry
Drugs
Diseases
GWAS
Age at first birth (
27089180
)
Age at first sexual intercourse (
34211149
27089180
)
Body mass index (
29273807
26426971
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Extremely high intelligence (
29520040
)
General cognitive ability (
29844566
)
General risk tolerance (MTAG) (
30643258
)
Glaucoma (
31959993
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Household income (MTAG) (
31844048
)
Intelligence (MTAG) (
29326435
)
Intraocular pressure (
31959993
29785010
)
Lateral thalamic nuclei volume (
34006833
)
Mean platelet volume (
32888494
)
Morning person (
30696823
)
Multisite chronic pain (
33830993
)
Refractive error (
32231278
)
Regular attendance at a gym or sports club (
29970889
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Sleep duration (short sleep) (
30846698
)
Smoking initiation (
33082346
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Apolipoprotein A1 levels (
32203549
)
Blood protein levels (
30072576
)
Brain morphology (MOSTest) (
32665545
)
Coronary artery disease (
29212778
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
HDL cholesterol levels (
32203549
)
Migraine (
27322543
)
Reticulocyte count (
32888494
)
Schizophrenia (
21682944
)
Small cell lung carcinoma (
28604730
)
Tetralogy of Fallot (
23297363
)
Type 1 diabetes (
34127860
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
7 interacting genes:
NRP1
NRP2
SHBG
SLC35G2
UBA1
UBC
VEGFA
27 interacting genes:
FGF1
FGF2
FGF4
FGF7
FGFR1
FLT1
GIPC1
KDR
L1CAM
NRP2
PGF
PLXNA1
PLXNB1
RPL27
SEMA3A
SEMA3B
SEMA3C
SEMA3F
SNCA
SNX5
SNX6
TGFBR1
TGFBR2
TGFBR3
USP9X
VEGFA
VEGFB
Entrez ID
6405
8829
HPRD ID
03079
03642
Ensembl ID
ENSG00000001617
ENSG00000099250
Uniprot IDs
C9JPG5
Q13275
Q59G50
A8K9V7
E9PEP6
O14786
Q59F20
Q6X907
PDB IDs
1KEX
2QQI
2QQM
2QQN
3I97
4DEQ
4RN5
5C7G
5IJR
5IYY
5J1X
5JGI
5JGQ
5JHK
5L73
6FMC
6FMF
6TKK
7JJC
7O1N
7P5U
8C5G
8PFE
9EOU
Enriched GO Terms of Interacting Partners
?
Vascular Endothelial Growth Factor Signaling Pathway
VEGF-activated Neuropilin Signaling Pathway
Vestibulocochlear Nerve Structural Organization
Dorsal Root Ganglion Morphogenesis
Sensory Neuron Axon Guidance
Facioacoustic Ganglion Development
Ventral Trunk Neural Crest Cell Migration
Neuropilin Signaling Pathway
Sympathetic Neuron Projection Guidance
Trigeminal Ganglion Development
Cranial Ganglion Development
Trunk Neural Crest Cell Migration
Positive Regulation Of Axon Extension Involved In Axon Guidance
Trigeminal Nerve Structural Organization
Neural Crest Cell Migration Involved In Autonomic Nervous System Development
Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus
Sympathetic Neuron Projection Extension
Vascular Endothelial Growth Factor Receptor Activity
Branchiomotor Neuron Axon Guidance
Bone Trabecula Formation
Hypothalamus Cell Migration
Coronary Artery Morphogenesis
Facial Nerve Structural Organization
Sympathetic Ganglion Development
Positive Regulation Of Endothelial Cell Proliferation
Coronary Vasculature Morphogenesis
Endothelial Cell Chemotaxis
Axon Extension Involved In Axon Guidance
Motor Neuron Migration
Semaphorin Receptor Activity
Commissural Neuron Axon Guidance
Positive Regulation Of Endothelial Cell Migration
Semaphorin Receptor Complex
Regulation Of Axon Extension Involved In Axon Guidance
Ganglion Development
Regulation Of Trophoblast Cell Migration
Anatomical Structure Arrangement
Neuron Migration
Regulation Of Endothelial Cell Proliferation
Retinal Ganglion Cell Axon Guidance
Heparin Binding
Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Motor Neuron Axon Guidance
Outflow Tract Septum Morphogenesis
Regulation Of Endothelial Cell Migration
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Positive Regulation Of Focal Adhesion Assembly
Positive Regulation Of Epithelial Cell Proliferation
Branching Involved In Blood Vessel Morphogenesis
Regulation Of Locomotion
Regulation Of Cell Migration
Positive Regulation Of Cell Migration
Regulation Of Cell Motility
Positive Regulation Of Cell Motility
Positive Regulation Of Locomotion
Semaphorin-plexin Signaling Pathway
Cell Migration
Enzyme-linked Receptor Protein Signaling Pathway
Heparin Binding
Chemotaxis
Cell Motility
Cell Surface Receptor Signaling Pathway
Locomotion
Vascular Endothelial Growth Factor Signaling Pathway
Tissue Morphogenesis
Positive Regulation Of Cell Division
Regulation Of Endothelial Cell Proliferation
Positive Regulation Of Endothelial Cell Proliferation
Regulation Of Epithelial Cell Proliferation
Anatomical Structure Formation Involved In Morphogenesis
Positive Regulation Of Epithelial Cell Proliferation
Regulation Of Chemotaxis
Neuropilin Binding
Angiogenesis
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Extracellular Region
Positive Regulation Of Cell Population Proliferation
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Semaphorin Receptor Binding
Lung Development
Anatomical Structure Morphogenesis
Regulation Of Cell Division
Positive Regulation Of Vasculature Development
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Endothelial Cell Migration
Regulation Of Endothelial Cell Migration
Positive Regulation Of Phosphate Metabolic Process
Chemoattractant Activity
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Response To Growth Factor
Developmental Growth Involved In Morphogenesis
Neuron Projection Guidance
Positive Regulation Of MAPK Cascade
Morphogenesis Of An Epithelium
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Cellular Response To Growth Factor Stimulus
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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