HIRA and ASF1A

Number of citations of the paper that reports this interaction (PubMedID 15621527)
0

Data Source:
HPRD (in vitro, in vivo)

		HIRA	ASF1A
Description		histone cell cycle regulator	anti-silencing function 1A histone chaperone
Image
GO Annotations	Cellular Component	HIR Complex Chromatin Nucleus Nucleoplasm PML Body Protein-containing Complex Extracellular Exosome	Chromatin Nucleus Nucleoplasm Chromosome Protein-containing Complex Site Of Double-strand Break
	Molecular Function	Transcription Corepressor Activity Protein Binding Nucleosome Binding Histone Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Chromatin Binding Protein Binding Histone Binding Histone Chaperone Activity
	Biological Process	Osteoblast Differentiation Chromatin Organization Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Gastrulation Anatomical Structure Morphogenesis Muscle Cell Differentiation Negative Regulation Of DNA-templated Transcription	Double-strand Break Repair Via Homologous Recombination Osteoblast Differentiation DNA Repair Chromatin Organization Nucleosome Assembly DNA Replication-dependent Chromatin Assembly DNA Damage Response Replication Fork Processing Muscle Cell Differentiation Protein Localization To Chromatin DNA Repair-dependent Chromatin Remodeling
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF) Replacement of protamines by nucleosomes in the male pronucleus	Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872)	Mean platelet volume ( 32888494) Multiple sclerosis ( 31604244) QT interval ( 19305408)
Interacting Genes		18 interacting genes: ASF1A CCNA2 CDK2 H2BC12 H2BC21 H2BC5 H3-3B HIRIP3 HNRNPD NFU1 OGT PAX7 RPA1 RPA2 TRIM55 TRIM63 UBE2I UPF1	32 interacting genes: ASF1B CHAF1A CHAF1B CHEK2 H3-3A H3-4 H3C3 H3C6 H4C1 H4C11 H4C12 H4C13 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HIRA HTATIP2 MCM2 PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17
Entrez ID		7290	25842
HPRD ID		02583	16459
Ensembl ID		ENSG00000100084	ENSG00000111875
Uniprot IDs		P54198	Q9Y294
PDB IDs		2I32 5YJE	1TEY 2I32 2IIJ 2IO5 3AAD 5C3I 6F0F 6F0G 6F0H 6ZUF 7LNY 7LO0 7V6Q 8BV1 8CJ1 8CJ2 8CJ3 8Z50
Enriched GO Terms of Interacting Partners?		Nucleus Nucleoplasm Telomere Organization Cellular Response To Nitric Oxide Cellular Response To Reactive Nitrogen Species Chromatin Organization Chromosome, Telomeric Region Response To Nitric Oxide Structural Constituent Of Chromatin Cyclin A2-CDK2 Complex Telomere Maintenance Telomeric DNA Binding Nucleosome DNA Replication Chromosome Organization G-rich Strand Telomeric DNA Binding Response To Stress DNA Replication Factor A Complex Regulation Of Chromosome Organization DNA Binding Regulation Of DNA Metabolic Process Mitotic G1 DNA Damage Checkpoint Signaling Macromolecule Metabolic Process Mitotic G1/S Transition Checkpoint Signaling DNA Repair Site Of Double-strand Break 3'-UTR-mediated MRNA Destabilization Nucleosome Assembly Protein Localization To Chromosome PML Body Innate Immune Response In Mucosa Regulation Of Chromatin Organization Nucleosome Organization Double-strand Break Repair Via Homologous Recombination Protein Heterodimerization Activity Recombinational Repair Mismatch Repair Mucosal Immune Response Chromatin Remodeling Nucleic Acid Metabolic Process Chromosome Organ Or Tissue Specific Immune Response Chromatin Cell Cycle Phase Transition Condensed Chromosome Cellular Response To Estradiol Stimulus Base-excision Repair Response To Electrical Stimulus DNA Metabolic Process Positive Regulation Of DNA Biosynthetic Process	Nucleosome Assembly Nucleosome Organization Protein-DNA Complex Assembly CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Structural Constituent Of Chromatin Nucleosome Regulation Of Megakaryocyte Differentiation Protein Localization To Chromosome, Centromeric Region Chromatin Organization Telomere Organization Chromatin Remodeling Chromosome, Telomeric Region Protein Localization To Chromatin Protein Heterodimerization Activity Negative Regulation Of Myeloid Cell Differentiation Protein Localization To Chromosome Protein-containing Complex Assembly Protein-containing Complex Chromosome Organization Protein-containing Complex Organization Chromosome Regulation Of Myeloid Cell Differentiation Cellular Component Assembly Regulation Of Hemopoiesis Extracellular Exosome Protein Localization To Organelle Nucleoplasm Negative Regulation Of Cell Differentiation DNA Binding DNA Replication-dependent Chromatin Assembly Regulation Of Cell Development Negative Regulation Of Developmental Process Intracellular Protein Localization Extracellular Region Organelle Organization RNA Binding Regulation Of Cell Differentiation Nucleus Regulation Of Multicellular Organismal Development Regulation Of Immune System Process CAF-1 Complex Regulation Of Developmental Process Histone Binding Protein Phosphorylation Protein Binding DNA Damage Response Phosphorylation RNA Polymerase II Core Promoter Sequence-specific DNA Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?