ASF1A and ST13

Number of citations of the paper that reports this interaction (PMID 15664198)
71

Data Source:
HPRD (in vitro)

		ASF1A	ST13
Gene Name		anti-silencing function 1A histone chaperone	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Protein Complex	Cytoplasm Cytosol Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Protein Binding Protein Domain Specific Binding Hsp70 Protein Binding Protein Binding, Bridging Protein Complex Binding DATP Binding Identical Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Chromatin Modification Negative Regulation Of Chromatin Silencing Muscle Cell Differentiation	Protein Folding Protein Homooligomerization Negative Regulation Of Protein Refolding Chaperone Cofactor-dependent Protein Refolding
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Cellular Senescence
Drugs
Diseases
GWAS		QT interval ( 19305408)
Protein-Protein Interactions		22 interactors: ASF1B CDAN1 CHAF1A CHAF1B CHEK2 H3F3A HIRA HIST1H3C HIST1H3E HIST1H4F HIST1H4L HIST3H3 HIST4H4 HTATIP2 PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17	18 interactors: ALB APOE ASF1A CD101 CDC42 CTRC CXCR2 F2 HSP90AA1 HSPA1A HSPA4 HSPA8 NOS3 OLFM2 PSEN1 SMAD2 TTR VAV2
Entrez ID		25842	6767
HPRD ID		16459	08426
Ensembl ID		ENSG00000111875	ENSG00000100380
Uniprot IDs		Q9Y294	B4E0U6 P50502 Q0IJ56
PDB IDs		1TEY 2I32 2IIJ 2IO5 3AAD	1UZS
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Nucleosome Assembly Chromatin Assembly Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Nucleosome Assembly Nucleosome Organization Chromatin Organization DNA Conformation Change Chromosome Organization DNA Methylation On Cytosine Chromatin Silencing At RDNA DNA Replication-independent Nucleosome Assembly Chromatin Silencing Cellular Macromolecular Complex Assembly Cellular Component Assembly Protein Complex Assembly DNA Methylation Negative Regulation Of Gene Expression, Epigenetic DNA Modification Organelle Organization Gene Silencing Histone H4-K20 Demethylation DNA Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Telomere Maintenance Regulation Of Megakaryocyte Differentiation Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Metabolic Process Gene Expression Methylation CENP-A Containing Nucleosome Assembly Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Exchange Histone Lysine Demethylation Histone Demethylation Protein Demethylation Regulation Of Chromatin Assembly Or Disassembly Centromere Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Demethylation	Response To External Stimulus Response To Stress Locomotion Negative Regulation Of Platelet Activation Protein Refolding Regulation Of Blood Coagulation Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Heat Regulation Of Cellular Response To Heat Cellular Response To Stimulus Regulation Of Platelet Activation Positive Regulation Of Immune System Process Anatomical Structure Morphogenesis Regulation Of Wound Healing Response To Unfolded Protein Response To Stimulus Protein Import Into Mitochondrial Outer Membrane Cellular Component Assembly Regulation Of Nitric-oxide Synthase Activity Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Vesicle-mediated Transport Regulation Of Apoptotic Process Establishment Of Localization In Cell Movement Of Cell Or Subcellular Component Endocytosis Regulation Of Cell Death Response To Wounding Negative Regulation Of Blood Coagulation Response To Temperature Stimulus Blood Coagulation Negative Regulation Of Coagulation Hemostasis Cellular Response To Heat Negative Regulation Of Wound Healing Regulation Of Cell Morphogenesis Cell Communication Cellular Localization Cell Migration Cell Surface Receptor Signaling Pathway Cell Development Regulation Of Immune System Process Regulation Of Oxidoreductase Activity Secretion By Cell Cardiovascular System Development Anatomical Structure Development Blood Vessel Development Transport Cell Motility Vasculature Development
Tagcloud ?		assembled caf chaperone chaperones dissect divergent enhances experiencing h4 hira histones involves mimetic newly nucleosomes organization phospho phosphorylated pocket restore shuttle stimulating supply tail timely tlk tlks tousled	carbapenemase centre cpe disseminated dublin ecdc encountered endemic enterobacteriaceae graded implementing intermittent internationally ireland irish klebsiella november outbreak oxa persisted pneumoniae producing pulsed referral sixteen st221 strict typing wards
Tagcloud (Difference) ?		assembled caf chaperone chaperones dissect divergent enhances experiencing h4 hira histones involves mimetic newly nucleosomes organization phospho phosphorylated pocket restore shuttle stimulating supply tail timely tlk tlks tousled	carbapenemase centre cpe disseminated dublin ecdc encountered endemic enterobacteriaceae graded implementing intermittent internationally ireland irish klebsiella november outbreak oxa persisted pneumoniae producing pulsed referral sixteen st221 strict typing wards
Tagcloud (Intersection) ?