ASF1A and CHAF1B

Number of citations of the paper that reports this interaction (PMID 11897662)
66

Data Source:
HPRD (in vivo)

		ASF1A	CHAF1B
Gene Name		anti-silencing function 1A histone chaperone	chromatin assembly factor 1, subunit B (p60)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Protein Complex	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol CAF-1 Complex Protein Complex
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Chromatin Binding Histone Binding Unfolded Protein Binding
	Biological Process	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Chromatin Modification Negative Regulation Of Chromatin Silencing Muscle Cell Differentiation	Reproduction DNA Replication DNA Repair DNA Replication-dependent Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Complex Assembly Cell Cycle Chromatin Assembly
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Cellular Senescence
Drugs
Diseases
GWAS		QT interval ( 19305408)
Protein-Protein Interactions		22 interactors: ASF1B CDAN1 CHAF1A CHAF1B CHEK2 H3F3A HIRA HIST1H3C HIST1H3E HIST1H4F HIST1H4L HIST3H3 HIST4H4 HTATIP2 PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17	9 interactors: APP ASF1A ASF1B CDK1 CDK2 CHAF1A HIST1H3E HIST3H3 RBBP4
Entrez ID		25842	8208
HPRD ID		16459	03147
Ensembl ID		ENSG00000111875
Uniprot IDs		Q9Y294	Q13112
PDB IDs		1TEY 2I32 2IIJ 2IO5 3AAD
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Nucleosome Assembly Chromatin Assembly Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Nucleosome Assembly Nucleosome Organization Chromatin Organization DNA Conformation Change Chromosome Organization DNA Methylation On Cytosine Chromatin Silencing At RDNA DNA Replication-independent Nucleosome Assembly Chromatin Silencing Cellular Macromolecular Complex Assembly Cellular Component Assembly Protein Complex Assembly DNA Methylation Negative Regulation Of Gene Expression, Epigenetic DNA Modification Organelle Organization Gene Silencing Histone H4-K20 Demethylation DNA Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Telomere Maintenance Regulation Of Megakaryocyte Differentiation Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Metabolic Process Gene Expression Methylation CENP-A Containing Nucleosome Assembly Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Exchange Histone Lysine Demethylation Histone Demethylation Protein Demethylation Regulation Of Chromatin Assembly Or Disassembly Centromere Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Demethylation	DNA Replication-dependent Nucleosome Assembly DNA Packaging Chromosome Organization DNA Conformation Change Nucleosome Assembly Chromatin Assembly Chromatin Organization Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Metabolic Process Regulation Of Gene Silencing DNA Replication-independent Nucleosome Assembly Nucleobase-containing Compound Metabolic Process Protein Complex Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Component Assembly Organelle Organization Cellular Nitrogen Compound Metabolic Process Chromatin Modification Cellular Macromolecular Complex Assembly Nitrogen Compound Metabolic Process DNA Replication Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription G2/M Transition Of Mitotic Cell Cycle Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA Repair Regulation Of Gene Expression, Epigenetic Response To Wounding Mitotic Cell Cycle Phase Transition Histone Phosphorylation Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Cellular Response To DNA Damage Stimulus Centrosome Cycle Regulation Of Cell Cycle Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of DNA Replication Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Gene Expression, Epigenetic Reproduction Pronuclear Fusion Regulation Of Mitotic Cell Cycle Response To Oxidative Stress Blood Coagulation
Tagcloud ?		assembled caf chaperone chaperones dissect divergent enhances experiencing h4 hira histones involves mimetic newly nucleosomes organization phospho phosphorylated pocket restore shuttle stimulating supply tail timely tlk tlks tousled
Tagcloud (Difference) ?		assembled caf chaperone chaperones dissect divergent enhances experiencing h4 hira histones involves mimetic newly nucleosomes organization phospho phosphorylated pocket restore shuttle stimulating supply tail timely tlk tlks tousled
Tagcloud (Intersection) ?