ASF1A

Gene Name		anti-silencing function 1A histone chaperone
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Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Protein Complex
	Molecular Function	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Chromatin Modification Negative Regulation Of Chromatin Silencing Muscle Cell Differentiation
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Cellular Senescence
Drugs
Diseases
GWAS		QT interval ( 19305408)
Protein-protein Interactions		22 interactors: ASF1B CDAN1 CHAF1A CHAF1B CHEK2 H3F3A HIRA HIST1H3C HIST1H3E HIST1H4F HIST1H4L HIST3H3 HIST4H4 HTATIP2 PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17
Entrez ID		25842
HPRD ID		16459
Ensembl ID		ENSG00000111875
Uniprot IDs		Q9Y294
PDB IDs		1TEY 2I32 2IIJ 2IO5 3AAD
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Nucleosome Assembly Chromatin Assembly Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Nucleosome Assembly Nucleosome Organization Chromatin Organization DNA Conformation Change Chromosome Organization DNA Methylation On Cytosine Chromatin Silencing At RDNA DNA Replication-independent Nucleosome Assembly Chromatin Silencing Cellular Macromolecular Complex Assembly Cellular Component Assembly Protein Complex Assembly DNA Methylation Negative Regulation Of Gene Expression, Epigenetic DNA Modification Organelle Organization Gene Silencing Histone H4-K20 Demethylation DNA Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Telomere Maintenance Regulation Of Megakaryocyte Differentiation Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Metabolic Process Gene Expression Methylation CENP-A Containing Nucleosome Assembly Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Exchange Histone Lysine Demethylation Histone Demethylation Protein Demethylation Regulation Of Chromatin Assembly Or Disassembly Centromere Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Demethylation
Tagcloud ?		assembled caf chaperone chaperones dissect divergent enhances experiencing h4 hira histones involves mimetic newly nucleosomes organization phospho phosphorylated pocket restore shuttle stimulating supply tail timely tlk tlks tousled