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TNNI2 and HNF4G
Number of citations of the paper that reports this interaction (PMID
15604093
)
36
Data Source:
BioGRID
(two hybrid)
TNNI2
HNF4G
Gene Name
troponin I type 2 (skeletal, fast)
hepatocyte nuclear factor 4, gamma
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Troponin Complex
Nucleoplasm
Molecular Function
Actin Binding
Protein Binding
Troponin T Binding
Sequence-specific DNA Binding Transcription Factor Activity
Steroid Hormone Receptor Activity
Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Zinc Ion Binding
Sequence-specific DNA Binding
Biological Process
Skeletal Muscle Contraction
Regulation Of Muscle Contraction
Muscle Filament Sliding
Positive Regulation Of Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Intracellular Receptor Signaling Pathway
Endocrine Pancreas Development
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Pathways
Striated Muscle Contraction
Regulation of beta-cell development
Generic Transcription Pathway
Regulation of gene expression in beta cells
Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Body mass index (
20935630
)
Breast cancer (
23535729
)
Obesity (
23563607
)
Urate levels (
23263486
)
Protein-Protein Interactions
13 interactors:
ACTB
CALM1
ESRRA
HNF4G
PKD2L1
RORB
TNNC1
TNNC2
TNNT1
TNNT3
TRIM55
TRIM63
UPF2
14 interactors:
COPS5
EIF3I
GAPDH
HAX1
HLF
NCOA1
NR0B2
NSD1
PNRC1
PNRC2
PRDX6
RANBP9
SRC
TNNI2
Entrez ID
7136
3174
HPRD ID
01843
06909
Ensembl ID
ENSG00000130598
ENSG00000164749
Uniprot IDs
P48788
F1D8Q4
Q14541
PDB IDs
1LV2
Enriched GO Terms of Interacting Partners
?
Muscle Contraction
Skeletal Muscle Contraction
Actin-myosin Filament Sliding
Muscle Filament Sliding
Muscle System Process
Musculoskeletal Movement
Actin-mediated Cell Contraction
Regulation Of Muscle Contraction
Actin Filament-based Movement
Striated Muscle Contraction
Cellular Response To Steroid Hormone Stimulus
Response To Steroid Hormone
Steroid Hormone Mediated Signaling Pathway
Cellular Response To Organic Cyclic Compound
Hormone-mediated Signaling Pathway
Response To Lipid
Cellular Response To Lipid
Response To Organic Cyclic Compound
Response To Hormone
Transcription Initiation From RNA Polymerase II Promoter
Intracellular Receptor Signaling Pathway
Substantia Nigra Development
Cellular Response To Hormone Stimulus
Regulation Of ATPase Activity
DNA-templated Transcription, Initiation
Actin Filament-based Process
Neural Nucleus Development
Organ Development
Regulation Of Muscle Filament Sliding Speed
Movement Of Cell Or Subcellular Component
Regulation Of Striated Muscle Contraction
Midbrain Development
Detection Of Chemical Stimulus Involved In Sensory Perception Of Sour Taste
Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Muscle Filament Sliding
Diaphragm Contraction
Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Regulation Of Osteoblast Differentiation
Cellular Response To Organic Substance
Signal Transduction
Amacrine Cell Differentiation
Regulation Of High Voltage-gated Calcium Channel Activity
Sensory Perception Of Sour Taste
Involuntary Skeletal Muscle Contraction
System Development
Skeletal Muscle Atrophy
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Response To Glucocorticoid
Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
RNA Biosynthetic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Biosynthetic Process
Response To Progesterone
Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose
Peptidyl-cysteine S-trans-nitrosylation
Intracellular Steroid Hormone Receptor Signaling Pathway
Positive Regulation Of Protein Kinase B Signaling
RNA Metabolic Process
Cellular Response To Progesterone Stimulus
Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Regulation Of Cellular Response To Drug
Peptidyl-amino Acid Modification
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Targeting To Mitochondrion
Exosomal Secretion
Response To Steroid Hormone
Regulation Of Protein Kinase B Signaling
Peptidyl-cysteine S-nitrosylation
Positive Regulation Of Integrin Activation
Positive Regulation Of Podosome Assembly
Regulation Of Response To Drug
Negative Regulation Of Mitochondrial Depolarization
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Organic Substance
Negative Regulation Of Protein Homooligomerization
Progesterone Receptor Signaling Pathway
Positive Regulation Of Female Receptivity
Regulation Of Podosome Assembly
Cellular Response To Hormone Stimulus
Male Mating Behavior
Regulation Of Caveolin-mediated Endocytosis
Mammary Gland Development
Tagcloud
?
5th
adcy9
ancestry
broader
classes
etiological
exploiting
extremes
generalizable
gnat2
h6pd
height
hip
hs6st3
igfbp4
influencing
loci
mrps33p4
obesity
overlap
percentiles
ppp2r2a
rptor
rsrc1
tails
trait
traits
waist
zzz3
Tagcloud (Difference)
?
5th
adcy9
ancestry
broader
classes
etiological
exploiting
extremes
generalizable
gnat2
h6pd
height
hip
hs6st3
igfbp4
influencing
loci
mrps33p4
obesity
overlap
percentiles
ppp2r2a
rptor
rsrc1
tails
trait
traits
waist
zzz3
Tagcloud (Intersection)
?