FOXJ1 and TWF2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		FOXJ1	TWF2
Gene Name		forkhead box J1	twinfilin actin-binding protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytoplasm Cytoskeleton Myofibril Lamellipodium Filopodium Growth Cone Stereocilium Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Sequence-specific DNA Binding Transcription Factor Activity	Actin Monomer Binding Protein Kinase C Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Central Tolerance Induction Negative Regulation Of Germinal Center Formation Positive Regulation Of Central B Cell Tolerance Induction Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Transcription From RNA Polymerase II Promoter Humoral Immune Response Spermatogenesis Pattern Specification Process Brain Development Actin Cytoskeleton Organization Negative Regulation Of NF-kappaB Transcription Factor Activity Activation Of Rho GTPase Activity Negative Regulation Of T Cell Differentiation In Thymus Establishment Of Apical/basal Cell Polarity Metanephric Part Of Ureteric Bud Development Negative Regulation Of T Cell Proliferation Cilium Assembly Negative Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of B Cell Activation Leukocyte Migration Cilium Morphogenesis Lung Epithelium Development Epithelium Development Left/right Pattern Formation Glomerular Parietal Epithelial Cell Development Positive Regulation Of Lung Ciliated Cell Differentiation	Positive Regulation Of Lamellipodium Assembly Positive Regulation Of Neuron Projection Development Cell Projection Organization Negative Regulation Of Actin Filament Polymerization Regulation Of Microvillus Length Regulation Of Actin Cytoskeleton Organization Sequestering Of Actin Monomers Positive Regulation Of Axon Extension Barbed-end Actin Filament Capping Cellular Response To Retinoic Acid Cellular Response To Growth Factor Stimulus
Pathways
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		7 interactors: NMRAL1 OIP5 RPUSD1 SLC37A3 THRA TRMT6 TWF2	6 interactors: ARHGDIA CHGB FOXJ1 ILK POT1 TERF2IP
Entrez ID		2302	11344
HPRD ID		03798	08464
Ensembl ID		ENSG00000129654	ENSG00000247596
Uniprot IDs		Q92949	Q6IBS0
PDB IDs			2VAC 2W0I
Enriched GO Terms of Interacting Partners?		Regulation Of Microvillus Length Negative Regulation Of Protein Complex Assembly Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Positive Regulation Of Female Receptivity Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Female Courtship Behavior Regulation Of Cell Projection Size Sequestering Of Actin Monomers Regulation Of Thyroid Hormone Mediated Signaling Pathway Regulation Of Protein Complex Assembly Regulation Of Female Receptivity	Telomere Capping Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Establishment Or Maintenance Of Apical/basal Cell Polarity Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Positive Regulation Of Catalytic Activity Positive Regulation Of Axonogenesis Negative Regulation Of Chromosome Organization Regulation Of Intracellular Signal Transduction Negative Regulation Of DNA Metabolic Process Regulation Of Cell Adhesion Kidney Morphogenesis Positive Regulation Of DNA Strand Elongation Positive Regulation Of Lung Ciliated Cell Differentiation Central Tolerance Induction Negative Regulation Of DNA Recombination At Telomere Glomerular Parietal Epithelial Cell Development Positive Regulation Of Central B Cell Tolerance Induction Regulation Of Cellular Component Organization Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Negative Regulation Of Cellular Metabolic Process Nephron Development Positive Regulation Of B Cell Tolerance Induction Negative Regulation Of Germinal Center Formation Regulation Of Axonogenesis Positive Regulation Of Cell Differentiation Kidney Epithelium Development Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Catalytic Activity Regulation Of Organelle Organization Establishment Or Maintenance Of Cell Polarity Glomerular Parietal Epithelial Cell Differentiation Telomere Formation Via Telomerase Negative Regulation Of Cell Migration Regulation Of Chromosome Organization Negative Regulation Of Cell Adhesion Positive Regulation Of Hydrolase Activity Negative Regulation Of Cell Motility Regulation Of Signal Transduction Positive Regulation Of Neuron Projection Development Negative Regulation Of Cellular Component Movement Protection From Non-homologous End Joining At Telomere Negative Regulation Of Locomotion Protein Localization To Chromosome, Telomeric Region
Tagcloud ?		aldh1 ciliated columnar exposes gynaecological hgsc hgscs krt5 krt7 layered lef1 mem membraneous nests outgrowths oviduct oviductal oviducts pax2 pseudostratified rcn1 scout scouts stathmin stins tubal walthard wcn wcns
Tagcloud (Difference) ?		aldh1 ciliated columnar exposes gynaecological hgsc hgscs krt5 krt7 layered lef1 mem membraneous nests outgrowths oviduct oviductal oviducts pax2 pseudostratified rcn1 scout scouts stathmin stins tubal walthard wcn wcns
Tagcloud (Intersection) ?