TSPO and CREB3L1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TSPO	CREB3L1
Gene Name		translocator protein (18kDa)	cAMP responsive element binding protein 3-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane Nuclear Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Androgen Binding Benzodiazepine Receptor Activity Cholesterol Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding CAMP Response Element Binding Sequence-specific DNA Binding
	Biological Process	Protein Targeting To Mitochondrion Steroid Biosynthetic Process Heme Biosynthetic Process Anion Transport Chloride Transport Lipid Transport Apoptotic Process Synaptic Transmission Aging Steroid Metabolic Process Cell Proliferation Glial Cell Migration Response To Manganese Ion Response To Vitamin B1 Positive Regulation Of Necrotic Cell Death Peripheral Nervous System Axon Regeneration Adrenal Gland Development Regulation Of Cholesterol Transport Response To Progesterone Negative Regulation Of Tumor Necrosis Factor Production Response To Testosterone Response To Drug Positive Regulation Of Apoptotic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Behavioral Response To Pain Regulation Of Steroid Biosynthetic Process Positive Regulation Of Mitochondrial Depolarization Positive Regulation Of Calcium Ion Transport Contact Inhibition Positive Regulation Of Glial Cell Proliferation Negative Regulation Of Glial Cell Proliferation Cellular Response To Lipopolysaccharide Cellular Response To Zinc Ion Cellular Hypotonic Response Positive Regulation Of Reactive Oxygen Species Metabolic Process	Transcription, DNA-templated Regulation Of Bone Mineralization Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs		Lorazepam Temazepam Eszopiclone Alprazolam Clorazepate Diazepam Triazolam Zaleplon Clonazepam Chlormezanone Zopiclone Flunitrazepam Ketazolam
Diseases
GWAS
Protein-Protein Interactions		3 interactors: BZRAP1 CREB3L1 DBI	23 interactors: C5 CREB3 CREB3L3 CREM DDIT3 FAM3C FBXW7 FXYD6 GPR25 JAGN1 MFSD5 NRM PGRMC1 PRKAB2 RUNX1T1 SLC30A8 SLC35B4 TMEM147 TMEM218 TMEM234 TSPO UBA1 UBE2D3
Entrez ID		706	90993
HPRD ID		15913	16751
Ensembl ID		ENSG00000100300	ENSG00000157613
Uniprot IDs		O76068 P30536	B2RA75 Q96BA8
PDB IDs
Enriched GO Terms of Interacting Partners?			Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein Response To Organic Substance ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Cellular Response To Stress Response To Stress Response To Unfolded Protein Regulation Of Lipid Biosynthetic Process Regulation Of Ion Homeostasis Response To Endoplasmic Reticulum Stress Ion Transport Negative Regulation Of Cell Cycle Signaling Cellular Response To Organic Substance Negative Regulation Of Biosynthetic Process Cell Communication Modification-dependent Protein Catabolic Process Regulation Of Cytokine Production Negative Regulation Of Determination Of Dorsal Identity Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Negative Regulation Of SREBP Signaling Pathway Granulocyte Colony-stimulating Factor Signaling Pathway UDP-xylose Transport Molybdate Ion Transport Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Cellular Metabolic Process Cellular Protein Catabolic Process Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Neuron Apoptotic Process Signal Transduction Proteasomal Protein Catabolic Process Inorganic Anion Transport Protein Catabolic Process Negative Regulation Of Triglyceride Biosynthetic Process Negative Regulation Of Macrophage Chemotaxis UDP-N-acetylglucosamine Transport Release From Viral Latency Regulation Of Transcription Involved In Anterior/posterior Axis Specification UDP-N-acetylglucosamine Transmembrane Transport Regulation Of Lipid Metabolic Process Positive Regulation Of Neuron Death Anion Transport Cellular Response To Stimulus Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Neutrophil Differentiation Response To Vitamin B1
Tagcloud ?		18f ages appl autoradiography cd68 cortex detecting ex fused happlond hippocampus images immunostaining microglia microglial mr pbr06 pet predetermined quantify striatum swe thy1 translocator uptake utility visualize visualizing wts	aggressive bladder candidate clearly colony downregulation hence highlights htra3 hypermethylation immunohistochemical interestingly invasive j82 mediates nuclei potentially predominately proposed public putative pyrosequencing set suppression suppressor tgf tissues verified
Tagcloud (Difference) ?		18f ages appl autoradiography cd68 cortex detecting ex fused happlond hippocampus images immunostaining microglia microglial mr pbr06 pet predetermined quantify striatum swe thy1 translocator uptake utility visualize visualizing wts	aggressive bladder candidate clearly colony downregulation hence highlights htra3 hypermethylation immunohistochemical interestingly invasive j82 mediates nuclei potentially predominately proposed public putative pyrosequencing set suppression suppressor tgf tissues verified
Tagcloud (Intersection) ?