TSPO and DBI

Number of citations of the paper that reports this interaction (PMID 7626442)
8

Data Source:
HPRD (in vivo, in vitro)

		TSPO	DBI
Gene Name		translocator protein (18kDa)	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane Nuclear Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Mitochondrion Endoplasmic Reticulum Golgi Apparatus Extracellular Vesicular Exosome Perinuclear Endoplasmic Reticulum
	Molecular Function	Androgen Binding Benzodiazepine Receptor Activity Cholesterol Binding	Lipid Binding Benzodiazepine Receptor Binding Long-chain Fatty Acyl-CoA Binding Protein Dimerization Activity
	Biological Process	Protein Targeting To Mitochondrion Steroid Biosynthetic Process Heme Biosynthetic Process Anion Transport Chloride Transport Lipid Transport Apoptotic Process Synaptic Transmission Aging Steroid Metabolic Process Cell Proliferation Glial Cell Migration Response To Manganese Ion Response To Vitamin B1 Positive Regulation Of Necrotic Cell Death Peripheral Nervous System Axon Regeneration Adrenal Gland Development Regulation Of Cholesterol Transport Response To Progesterone Negative Regulation Of Tumor Necrosis Factor Production Response To Testosterone Response To Drug Positive Regulation Of Apoptotic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Behavioral Response To Pain Regulation Of Steroid Biosynthetic Process Positive Regulation Of Mitochondrial Depolarization Positive Regulation Of Calcium Ion Transport Contact Inhibition Positive Regulation Of Glial Cell Proliferation Negative Regulation Of Glial Cell Proliferation Cellular Response To Lipopolysaccharide Cellular Response To Zinc Ion Cellular Hypotonic Response Positive Regulation Of Reactive Oxygen Species Metabolic Process	Behavioral Fear Response Hair Follicle Development Triglyceride Metabolic Process Transport Learning Or Memory Protein Palmitoylation Lateral Ventricle Development Phosphatidylcholine Acyl-chain Remodeling Long-term Synaptic Potentiation
Pathways
Drugs		Lorazepam Temazepam Eszopiclone Alprazolam Clorazepate Diazepam Triazolam Zaleplon Clonazepam Chlormezanone Zopiclone Flunitrazepam Ketazolam
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		3 interactors: BZRAP1 CREB3L1 DBI	10 interactors: DUSP23 GSK3B MAP1LC3B NIPSNAP1 NSFL1C PPCDC RAD23A RAD23B TSPO UBXN2A
Entrez ID		706	1622
HPRD ID		15913	08832
Ensembl ID		ENSG00000100300	ENSG00000155368
Uniprot IDs		O76068 P30536	B8ZWD1 P07108
PDB IDs			2CB8 2FJ9
Enriched GO Terms of Interacting Partners?			Cellular Response To Stress Autophagic Vacuole Assembly Macroautophagy Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Vacuole Organization Nuclear Envelope Reassembly Regulation Of Protein Catabolic Process Membrane Fusion Response To Nutrient Levels Cellular Response To Starvation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Extracellular Stimulus Ubiquitin-dependent Protein Catabolic Process Autophagy Modification-dependent Protein Catabolic Process Cellular Response To Nutrient Levels Response To Starvation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Protein Catabolic Process Cellular Response To Extracellular Stimulus Response To Stress Cellular Macromolecule Catabolic Process Nuclear Envelope Organization Catabolic Process Response To External Stimulus Golgi Organization Nucleotide-excision Repair Negative Regulation Of Type B Pancreatic Cell Development Nucleotide-excision Repair, DNA Damage Recognition Superior Temporal Gyrus Development Organelle Assembly Nucleus Organization Re-entry Into Mitotic Cell Cycle Response To Vitamin B1 Negative Regulation Of Neuron Maturation Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Positive Regulation Of Necrotic Cell Death Cellular Response To Interleukin-3 Regulation Of Proteolysis Proteolysis Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Neuron Maturation Cellular Metabolic Process Protein Localization To Microtubule Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Dendrite Morphogenesis
Tagcloud ?		18f ages appl autoradiography cd68 cortex detecting ex fused happlond hippocampus images immunostaining microglia microglial mr pbr06 pet predetermined quantify striatum swe thy1 translocator uptake utility visualize visualizing wts	abolishes availability bear box cdna cloned contains dead diminishes display fibroblast identity kb message mitogenic nontransforming notch overexpressed place recognize repeats solely take terminally terminus transcript transform transforming truncated
Tagcloud (Difference) ?		18f ages appl autoradiography cd68 cortex detecting ex fused happlond hippocampus images immunostaining microglia microglial mr pbr06 pet predetermined quantify striatum swe thy1 translocator uptake utility visualize visualizing wts	abolishes availability bear box cdna cloned contains dead diminishes display fibroblast identity kb message mitogenic nontransforming notch overexpressed place recognize repeats solely take terminally terminus transcript transform transforming truncated
Tagcloud (Intersection) ?