TSPO and TSPOAP1

Number of citations: 0 (PubMedID 9915832)
Data Source: BioGRID (pull down), HPRD (two hybrid, in vitro)

		TSPO	TSPOAP1
Name		translocator protein	TSPO associated protein 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane Mitochondrial Membrane Extracellular Exosome	Cytoplasm Mitochondrion Cytosol Calyx Of Held Glutamatergic Synapse
	Molecular Function	Androgen Binding Protein Binding Benzodiazepine Receptor Activity Cholesterol Binding Transmembrane Transporter Binding Cholesterol Transfer Activity	Protein Binding Benzodiazepine Receptor Binding Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels
	Biological Process	Protein Targeting To Mitochondrion Steroid Biosynthetic Process C21-steroid Hormone Biosynthetic Process Heme Biosynthetic Process Monoatomic Ion Transport Monoatomic Anion Transport Chloride Transport Lipid Transport Steroid Metabolic Process Glial Cell Migration Response To Xenobiotic Stimulus Response To Manganese Ion Response To Vitamin B1 Peripheral Nervous System Axon Regeneration Sterol Transport Adrenal Gland Development Negative Regulation Of Protein Ubiquitination Regulation Of Cholesterol Transport Response To Progesterone Negative Regulation Of Tumor Necrosis Factor Production Response To Testosterone Regulation Of Cell Population Proliferation Cholesterol Homeostasis Positive Regulation Of Apoptotic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Response To Pain Behavioral Response To Pain Response To Axon Injury Regulation Of Steroid Biosynthetic Process Positive Regulation Of Mitochondrial Depolarization Positive Regulation Of Calcium Ion Transport Contact Inhibition Positive Regulation Of Glial Cell Proliferation Negative Regulation Of Glial Cell Proliferation Positive Regulation Of Programmed Necrotic Cell Death Cellular Response To Lipopolysaccharide Cellular Response To Zinc Ion Cellular Hypotonic Response Establishment Of Protein Localization To Mitochondrion Maintenance Of Protein Location In Mitochondrion Negative Regulation Of Mitophagy Negative Regulation Of ATP Metabolic Process Response To Acetylcholine Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Corticosterone Secretion	Neuromuscular Synaptic Transmission Regulation Of Neurotransmitter Secretion Regulation Of Presynaptic Cytosolic Calcium Ion Concentration
Pathways		Pregnenolone biosynthesis	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Pregnenolone biosynthesis Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle
Drugs		Chlormezanone Zopiclone	None
GWAS		Metabolite levels ( 23823483 ) Monocyte count ( 27863252 32888494 ) Monocyte percentage of white cells ( 27863252 32888494 ) White blood cell count ( 32888494 )	No GWAS studies recorded
Novel Interactors		1 novel interactors: TSPAN15	None recorded
Interacting Genes		17 interacting genes: AMIGO1 CLEC10A CREB3L1 DBI FAM209A FCER1G ICAM3 KCNF1 LEUTX LHFPL5 LYPD5 MEOX2 NCR3LG1 PVR TMEM14B TMEM9 TSPOAP1	19 interacting genes: ANKRD11 ARNT2 BEND5 CACNA1A CADPS2 CEP76 DISC1 DLGAP2 DLX2 GPRASP2 KHDRBS1 KIF1A MVP NDE1 RAPGEF4 REL TCF4 TSC22D4 TSPO
Entrez ID		706	9256
HPRD ID		15913	09832
Ensembl ID		ENSG00000100300	ENSG00000005379
Uniprot IDs		O76068 P30536	A7E2C5 B2RUT8 B7ZVZ7 O95153 X5DQQ3
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Benzodiazepine Receptor Binding	Kinesin Complex Synapse Secretory Granule Localization Establishment Of Vesicle Localization Vesicle Localization Glial Cell Migration Hematopoietic Stem Cell Homeostasis