TGFB1 and GREB1

  • Number of citations: 0 (PubMedID 25640309)
  • Data Source: BioGRID (two hybrid)

TGFB1

GREB1

Name transforming growth factor beta 1 growth regulating estrogen receptor binding 1
Structure PDB 1KLA No pdb structure
GO Annotations Cellular Component
Molecular Function None
Biological Process
Pathways
Drugs None
Diseases None
GWAS
  • Alanine aminotransferase levels ( 34315874 )
  • Aspartate aminotransferase levels ( 34315874 )
  • Colorectal cancer ( 24836286 27145994 )
  • Colorectal cancer or advanced adenoma ( 30510241 )
  • Coronary artery disease ( 28714974 29212778 33020668 )
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975 )
  • Hematuria ( 30476138 )
  • Hematuria (mild) ( 30476138 )
  • Hematuria (moderate to severe) ( 30476138 )
  • Platelet count ( 32888494 )
  • Preterm birth (maternal effect) ( 28877031 )
  • Pulse pressure ( 30578418 )
  • Type 2 diabetes ( 31049640 )
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653 )
  • Diisocyanate-induced asthma ( 25918132 )
  • Endometriosis ( 23104006 28537267 )
  • Gynecologic disease (multivariate analysis) ( 31488892 )
  • High density lipoprotein cholesterol levels ( 30108155 )
  • Inferior parietal cortex volume ( 31530798 )
  • LDL cholesterol levels in HIV infection ( 33109212 )
  • Obesity-related traits ( 23251661 )
  • Severe insulin-resistant type 2 diabetes ( 34737425 )
  • Uterine fibroids ( 30194396 31649266 )
Interacting Genes 99 interacting genes: ACVRL1 ADAMTSL4 AGR3 ANGPTL4 APC APP AURKA AXIN2 BCAS3 BCL10 BGN BLID BMP2 BMP3 BMPR1A BUB1 CATSPER1 CCDC33 CCL3 CCL5 CCN2 CDKN2A CFTR COL2A1 CST6 CYSRT1 DAXX DCN DIRAS3 DLC1 DPT EGFR EIF3I ENG ERBB2 FBXW7 FCHO1 FCN1 FKBP1A FMOD FNTA GREB1 HOXA1 HOXC6 ITGAV ITGB6 ITGB8 KLK5 KLK7 KLK9 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP4-11 LAMTOR5 LCE1A LCE1C LCE1D LCE1F LCE2B LCE2C LCE3A LCE3B LCE3D LCE5A LPXN LTBP1 LTBP3 LTBP4 MCC MEOX2 MLH3 MMP2 MTA3 NSD3 P4HB PDGFRL PDLIM2 POU4F2 PRSS50 PSMC3IP PZP RAPGEF3 SCGB3A1 SDC2 SNAI1 SPARC ST14 TGFB2 TGFBR1 TGFBR2 TGFBR3 THBS1 THRSP TLR2 UBC VASN VTN YWHAE 12 interacting genes: BCAR3 CASP8 CDKN2C ESR1 HMMR HRAS LSP1 PALB2 RB1CC1 SMAD4 TGFB1 XRCC3
Entrez ID 7040 9687
HPRD ID 01821 13611
Ensembl ID ENSG00000105329 ENSG00000196208
Uniprot IDs A0A499FJK2 P01137 Q4ZG55
PDB IDs 1KLA 1KLC 1KLD 3KFD 4KV5 5FFO 5VQP 6OM2 6P7J 7Y1R 7Y1T 8UDZ 8VSC 8VSD 9FDY 9FKP Not available
GO Terms Enriched among Interactors