GREB1

Name	growth regulating estrogen receptor binding 1
Structure	No pdb structure
Interactors	12 interactors: BCAR3 CASP8 CDKN2C ESR1 HMMR HRAS LSP1 PALB2 RB1CC1 SMAD4 TGFB1 XRCC3
GO Annotations	Cellular Component	Nucleoplasm Membrane Extracellular Exosome
	Biological Process	Morphogenesis Of An Epithelium
Pathways	Estrogen-dependent gene expression
GWAS	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653 ) Diisocyanate-induced asthma ( 25918132 ) Endometriosis ( 23104006 28537267 ) Gynecologic disease (multivariate analysis) ( 31488892 ) High density lipoprotein cholesterol levels ( 30108155 ) Inferior parietal cortex volume ( 31530798 ) LDL cholesterol levels in HIV infection ( 33109212 ) Obesity-related traits ( 23251661 ) Severe insulin-resistant type 2 diabetes ( 34737425 ) Uterine fibroids ( 30194396 31649266 )
Entrez ID	9687
HPRD ID	13611
Ensembl ID	ENSG00000196208
Uniprot IDs	Q4ZG55
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Regulation Of MiRNA Metabolic Process Extrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Cell Population Proliferation Positive Regulation Of Fibroblast Proliferation Regulation Of Intracellular Signal Transduction Positive Regulation Of MiRNA Metabolic Process Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of MiRNA Transcription Positive Regulation Of Extracellular Matrix Assembly Positive Regulation Of Signal Transduction Branch Elongation Of An Epithelium Regulation Of Fibroblast Proliferation Hyaluronan Catabolic Process Regulation Of Cell Population Proliferation Positive Regulation Of Macrophage Differentiation Regulation Of MAPK Cascade Response To Estradiol Positive Regulation Of Cell Communication Positive Regulation Of Signaling Axis Elongation Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Cardiac Muscle Cell Differentiation Negative Regulation Of Cell Population Proliferation Developmental Growth Branching Morphogenesis Of An Epithelial Tube Uterus Development Glycosaminoglycan Catabolic Process Regulation Of Extracellular Matrix Assembly Hyaluronan Metabolic Process Regulation Of Macrophage Differentiation Morphogenesis Of A Branching Epithelium Negative Regulation Of MiRNA Transcription Positive Regulation Of Extracellular Matrix Organization Animal Organ Development Morphogenesis Of A Branching Structure Negative Regulation Of Cell Growth Positive Regulation Of MAPK Cascade Apoptotic Process Anatomical Structure Morphogenesis Negative Regulation Of Programmed Cell Death Regulation Of Signal Transduction Endoderm Development Positive Regulation Of Cell Population Proliferation Protein-membrane Adaptor Activity Programmed Cell Death Cell Death Response To Stress