TGFA and GORASP1

Number of citations of the paper that reports this interaction (PMID 11739402)
23

Data Source:
BioGRID (pull down)
HPRD (two hybrid, in vivo)

		TGFA	GORASP1
Gene Name		transforming growth factor, alpha	golgi reassembly stacking protein 1, 65kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	Golgi Membrane Golgi Apparatus
	Molecular Function	Glycoprotein Binding Epidermal Growth Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Activation Of MAPK Activity Angiogenesis Epidermal Growth Factor Receptor Signaling Pathway Cell Proliferation Wound Healing Response To Drug Negative Regulation Of Apoptotic Process Positive Regulation Of Epidermal Growth Factor-activated Receptor Activity Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Epithelial Cell Proliferation Mammary Gland Alveolus Development	Mitotic Cell Cycle Golgi Organization Protein Transport Negative Regulation Of Dendrite Morphogenesis
Pathways			Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Longevity ( 20834067) Neutrophil count ( 21507922) Obesity-related traits ( 23251661)
Protein-Protein Interactions		15 interactors: ADAM10 ADAM17 EGFR ELANE ERBB2 ERBB4 GORASP1 GORASP2 MAGI2 MAGI3 NKD2 RHBDF1 SDCBP SGTA SNTA1	14 interactors: AGPS CASP3 CASP7 CDK1 GOLGA2 HIPK3 LONRF1 MAPK6 PLK1 PRKD2 SCRN1 TGFA TMED2 TMED3
Entrez ID		7039	64689
HPRD ID		07522	06038
Ensembl ID		ENSG00000163235	ENSG00000114745
Uniprot IDs		E7EPT6 F8VNR3 P01135	B3KPY8 B4E1H8 Q9BQQ3
PDB IDs		1GK5 1MOX 1YUF 1YUG 2TGF 3E50 3TGF 4TGF
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of MAPK Cascade Neurotrophin Signaling Pathway Locomotion Positive Regulation Of Kinase Activity Positive Regulation Of Phosphorylation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Transferase Activity Regulation Of Signal Transduction Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component PMA-inducible Membrane Protein Ectodomain Proteolysis Regulation Of MAPK Cascade Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Locomotion Regulation Of Signaling Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Component Movement Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Positive Regulation Of Cell Proliferation Cell Migration Positive Regulation Of Protein Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Collagen Catabolic Process Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Growth Cell Motility Positive Regulation Of Protein Modification Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of T Cell Chemotaxis Regulation Of Cell Proliferation Collagen Metabolic Process Regulation Of ERBB Signaling Pathway Positive Regulation Of Catalytic Activity Multicellular Organismal Macromolecule Metabolic Process Cellular Response To Growth Factor Stimulus Generation Of Neurons Regulation Of Cell Migration Multicellular Organismal Metabolic Process	Peptidyl-serine Phosphorylation Regulation Of Catalytic Activity Regulation Of Protein Phosphorylation Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Positive Regulation Of Protein Metabolic Process Positive Regulation Of Mitotic Cell Cycle Regulation Of Protein Kinase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Regulation Of Kinase Activity Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Proteolysis Protein Localization To Chromosome Positive Regulation Of Catalytic Activity Regulation Of Cell Death Negative Regulation Of Cell Death G2 DNA Damage Checkpoint Mitotic Nuclear Envelope Disassembly Cell Death Death Negative Regulation Of Protein Kinase Activity Positive Regulation Of Mitotic Nuclear Division Nuclear Envelope Disassembly Negative Regulation Of Kinase Activity Peptidyl-threonine Phosphorylation Regulation Of MAPK Cascade Regulation Of Proteolysis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of MAP Kinase Activity Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Pronuclear Fusion Positive Regulation Of Protein Phosphorylation Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Transferase Activity Protein Phosphorylation Nuclear Envelope Organization Negative Regulation Of Protein Phosphorylation Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Execution Phase Of Apoptosis
Tagcloud ?		alleles bcl3 cleft clefts conditional covariates d19s178 definitive disequilibrium ethnic incorporated incorporating lip modestly modifiers odds offspring parent permitting probands proto stratification tdt tgfb3 thra1 transforming transmission trios utilizing	adc aldh1l1 ankrd28 bhlhe40 cggbp1 ctdspl ephb1 fbln2 fgd5 foxp1 gnai2 iqsec1 itga itga9 loc285205 loc285375 lrrc3b lrrn1 mitf nkiras1 noti rbsp3 rpl15 rpl32 thrb ttc21 ube2e2 vhl wnt7a
Tagcloud (Difference) ?		alleles bcl3 cleft clefts conditional covariates d19s178 definitive disequilibrium ethnic incorporated incorporating lip modestly modifiers odds offspring parent permitting probands proto stratification tdt tgfb3 thra1 transforming transmission trios utilizing	adc aldh1l1 ankrd28 bhlhe40 cggbp1 ctdspl ephb1 fbln2 fgd5 foxp1 gnai2 iqsec1 itga itga9 loc285205 loc285375 lrrc3b lrrn1 mitf nkiras1 noti rbsp3 rpl15 rpl32 thrb ttc21 ube2e2 vhl wnt7a
Tagcloud (Intersection) ?