TERF2 and TALDO1

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		TERF2	TALDO1
Gene Name		telomeric repeat binding factor 2	transaldolase 1
Image
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nuclear Chromosome, Telomeric Region Male Germ Cell Nucleus Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Mre11 Complex	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Chromatin Binding Double-stranded Telomeric DNA Binding Protein Binding Protein C-terminus Binding Telomeric DNA Binding Protein Homodimerization Activity	Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate Glyceronetransferase Activity
	Biological Process	Telomere Maintenance Age-dependent Telomere Shortening In Utero Embryonic Development Telomere Maintenance Via Telomerase Cell Cycle Telomere Capping Telomeric Loop Formation Protection From Non-homologous End Joining At Telomere Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Protein Localization To Chromosome, Telomeric Region Cellular Senescence	Carbohydrate Metabolic Process Xylulose Biosynthetic Process Pentose-phosphate Shunt Energy Reserve Metabolic Process Pathogenesis Small Molecule Metabolic Process
Pathways		Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis	Integration of energy metabolism Insulin effects increased synthesis of Xylulose-5-Phosphate Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates Pentose phosphate pathway (hexose monophosphate shunt)
Drugs
Diseases
GWAS
Protein-Protein Interactions		55 interactors: AFAP1L2 ANXA5 APEX1 ASS1 ATM BANP BLM CCDC137 CTBP1 DCLRE1B DDX21 DDX24 DDX39A EP300 GNMT H2AFX HDGFRP2 HEXIM1 HEXIM2 HMGB1 HMGN1 HMGN2 HMGN3 HMGN4 LANCL2 LYAR MAGOHB NAIF1 NASP NCL NUMA1 NXNL1 OCM2 ORC3 ORC6 POT1 PPM1G PRMT1 PTMA RNF113A RPL13 RPRD1B SET SIAH1 SP100 SRSF6 TALDO1 TERF2IP TINF2 TMSB10 TOR1AIP1 WDR4 WRN XRCC6 ZC3H18	5 interactors: LSM8 TERF1 TERF2 TERF2IP ZHX1
Entrez ID		7014	6888
HPRD ID		03610	03640
Ensembl ID		ENSG00000132604	ENSG00000177156
Uniprot IDs		Q15554	F2Z393 P37837
PDB IDs		1H6P 1VF9 1VFC 1W0U 1XG1 3BU8 3BUA 3K6G 3SJM 4M7C	1F05
Enriched GO Terms of Interacting Partners?		Telomere Maintenance Chromosome Organization Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process DNA Metabolic Process Organelle Organization DNA Replication Chromatin Organization Negative Regulation Of Chromosome Organization Cellular Response To DNA Damage Stimulus DNA Conformation Change Telomere Capping Cell Cycle Cellular Metabolic Process DNA Recombination Telomere Maintenance Via Telomere Lengthening Double-strand Break Repair Negative Regulation Of Telomere Maintenance RNA Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process DNA Repair Chromatin Modification Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Chromosome Organization Cellular Response To Stress Cellular Response To Ionizing Radiation Regulation Of Telomere Maintenance Response To Ionizing Radiation Regulation Of Cell Cycle DNA Duplex Unwinding DNA Geometric Change Regulation Of Nitrogen Compound Metabolic Process Double-strand Break Repair Via Homologous Recombination V(D)J Recombination Recombinational Repair Regulation Of Metabolic Process Cell Cycle Process Protection From Non-homologous End Joining At Telomere Negative Regulation Of DNA Metabolic Process Homeostatic Process Negative Regulation Of Nucleic Acid-templated Transcription Gene Expression Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase	Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Protection From Non-homologous End Joining At Telomere Telomere Capping Telomere Maintenance Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Replicative Cell Aging Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Chromosome Organization Protein Localization To Chromosome DNA Replication Negative Regulation Of DNA Replication Cell Aging Negative Regulation Of DNA Recombination At Telomere Nucleobase-containing Compound Metabolic Process Regulation Of DNA Replication Negative Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Organelle Organization Nitrogen Compound Metabolic Process Chromosome Organization DNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Biosynthetic Process Homeostatic Process Aging Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Organelle Organization Positive Regulation Of Microtubule Polymerization Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Telomerase Activity Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Process Protein Localization To Organelle Regulation Of Cellular Component Organization
Tagcloud ?		anticancer catalytic cloned compensate division elucidated encoding erosion fusions generally homolog immortality length neoplasms p80 protection repeat repeats repressed ribonucleoprotein telomerase telomere telomeric tep1 terc terf1 tert upregulated withdrawal	11p15 chromosome d11s922 ecori equivalents exons fragment harboring hybrids integrity intermediates locus mapped mapping p13 p15 pentose placed pseudogene pter repetitive somatic southern terminating transcriptase wi
Tagcloud (Difference) ?		anticancer catalytic cloned compensate division elucidated encoding erosion fusions generally homolog immortality length neoplasms p80 protection repeat repeats repressed ribonucleoprotein telomerase telomere telomeric tep1 terc terf1 tert upregulated withdrawal	11p15 chromosome d11s922 ecori equivalents exons fragment harboring hybrids integrity intermediates locus mapped mapping p13 p15 pentose placed pseudogene pter repetitive somatic southern terminating transcriptase wi
Tagcloud (Intersection) ?