TEK and PIK3R1

  • Number of citations of the paper that reports this interaction (PMID 10521483)
  • 35
  • Data Source:
  • HPRD (in vitro, two hybrid, in vivo)

TEK

PIK3R1

Gene Name TEK tyrosine kinase, endothelial phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease biomarkers ( 23419831)
  • Menarche (age at onset) ( 23599027)
Protein-Protein Interactions 20 interactors: ANGPT1 ANGPT2 ANGPT4 ANGPTL1 APP DOK2 DOK4 GRB14 GRB2 GRB7 IKBKG PIK3R1 PTPN11 PTPRB SHC1 SOCS1 STAT5A STAT5B TIE1 TNIP2 149 interactors: ABL1 ADAM12 ADAMTS2 AGAP2 AKT1 ALK ANK3 ARAF ARHGAP1 ARHGAP17 ARHGAP32 AXL BCAR1 BRCA1 CBL CBLB CCL14 CD19 CD22 CD28 CD2AP CD3E CD4 CD40 CD5 CD7 CDC42 CDH2 CHRNA7 CRK CRKL CSF1R CSF2RA CTLA4 CTNNB1 CXCL2 CYP4A11 DLX2 DNM1 DOK1 EGFR EPHA2 EPOR ERAS ERBB2 ERBB3 ESR1 EZR FASLG FCGR2A FES FGFR1 FYN GAB1 GAB2 GAB3 GHR GRB2 GSK3B GSPT1 GTF2H1 HCK HCST HDAC1 HGS HOXA1 HRAS HTT IFNAR1 IGF1R IL13 IL1R1 IL1RAP IL2RB IL7R INPP4A INSR IRS1 IRS2 IRS4 ITSN1 JAK1 JAK2 JAK3 KHDRBS1 KIT LAT LCK LCP2 MAPK8 MET MME MST1R NFKBIA NTRK1 NTRK2 NUP85 PDGFRA PDGFRB PECAM1 PFN1 PIK3AP1 PIK3CA PIK3CB PIK3CD PPM1A PSEN1 PSMB5 PTK2 PTK2B PTPN11 PTPN6 RAC1 RASA1 RB1 RET RRAS2 SH3KBP1 SHB SHC1 SLC9A2 SOCS1 SOCS6 SOCS7 SRC SSTR2 SYK SYN1 TEC TEK TGFBR1 TGFBR2 TIE1 TLR2 TOM1L1 TRAT1 TSHR TTR TUB TUBA1B TUBG1 TYK2 TYRO3 VAV1 VAV3 WAS WASF3 WBP11 YWHAG
Entrez ID 7010 5295
HPRD ID 02571 01381
Ensembl ID ENSG00000120156 ENSG00000145675
Uniprot IDs Q02763 Q59HG2 P27986
PDB IDs 1FVR 2GY5 2GY7 2OO8 2OSC 2P4I 2WQB 3BEA 3L8P 4K0V 1A0N 1AZG 1H9O 1PBW 1PHT 1PIC 1PKS 1PKT 2IUG 2IUH 2IUI 2RD0 2V1Y 3HHM 3HIZ 3I5R 3I5S 4A55
Enriched GO Terms of Interacting Partners?
Tagcloud ?
amplify  blk  bpk  cdnas  cmet  degenerate  eck  f1  fer  fes  fgr  flk  fyn  hck  kit  lacked  lin  ly6a  ptks  rtk  rtks  ryk  sca  sixteen  sorted  sorter  stk  turned  tyk 
16q  1q  affymetrix  classic  clustering  clusters  cytoskeleton  distinguished  epithelium  fresh  frozen  golm1  gpr137b  hierarchical  ilc  lcis  lobular  mastectomy  microarrays  microdissected  obligate  personalize  precursor  prophylactic  supervised  transcriptomic  triplets  u133a  unsupervised 
Tagcloud (Difference) ?
amplify  blk  bpk  cdnas  cmet  degenerate  eck  f1  fer  fes  fgr  flk  fyn  hck  kit  lacked  lin  ly6a  ptks  rtk  rtks  ryk  sca  sixteen  sorted  sorter  stk  turned  tyk 
16q  1q  affymetrix  classic  clustering  clusters  cytoskeleton  distinguished  epithelium  fresh  frozen  golm1  gpr137b  hierarchical  ilc  lcis  lobular  mastectomy  microarrays  microdissected  obligate  personalize  precursor  prophylactic  supervised  transcriptomic  triplets  u133a  unsupervised 
Tagcloud (Intersection) ?