ELOA and CCDC57

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ELOA	CCDC57
Description		elongin A	coiled-coil domain containing 57
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Elongin Complex Site Of DNA Damage	Cytoplasm Centrosome Centriole Spindle Cytoskeleton Spindle Microtubule Centriolar Satellite
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Transcription Elongation By RNA Polymerase II	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Centriole Replication Positive Regulation Of Mitotic Cell Cycle Cilium Assembly
Pathways		Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)
Interacting Genes		58 interacting genes: AXIN2 BACH2 BRCA1 CBY2 CCDC57 CDR2L CEP57L1 CEP70 CNTROB CUL5 DLGAP1-AS2 ELOB ERCC6 EVI5 FAM9B FCHO1 FXR1 GMCL1 GOLGA6A GRIPAP1 HIVEP1 HOMEZ JAKMIP2 KANK2 KLHL2 KRT40 KRTAP10-3 KXD1 LMNA LZTS1 MCC MDFI MED21 MID1 MID2 NAB2 NACC1 NAF1 NFKBID NINL OGT PER2 PLK4 PPFIA1 PRDM6 PRMT5 RABEP1 RAD54B RAP1A REXO1 RNF10 SIRPA SPECC1L TNIP1 TP53BP2 TRIM37 TRIM54 ZNF792	148 interacting genes: ABI1 ABI2 ABLIM1 AMOTL2 ANKRD23 AQP1 ARID5A ARL4A AXIN1 BCAR3 BEX2 C19orf44 CATSPERT CBX8 CBY2 CCDC120 CCDC33 CDC20B CEP57L1 CFAP53 COIL CRTC2 CWF19L2 DCLK2 DISC1 DTX2 ECPAS EFHC2 EIF3D EIF4G1 ELOA EMILIN3 ESS2 FAM107A FAM161A FAM161B FAM228A FAM50B FAM90A1 FH FOXD4L1 FTO GFAP GIGYF1 GPBP1 GPKOW GRPEL1 HAUS1 HBA2 HDX IHO1 IKZF3 INCA1 INTS2 JRK KANK2 KIAA0408 KLF1 KLF15 KPRP KRT4 KRT76 KRTAP13-2 KRTAP13-3 LENG1 LINC00526 LZTS1 MAD1L1 MDM1 MFAP1 MT1E MYOZ3 NAB2 NAPRT NCOA5 NELFE NME4 NUMA1 PAK5 PER1 POM121 PPHLN1 PPP1R18 PRAM1 PRDM6 PROSER3 PRPF18 PRPF31 PRR3 PSMB4 PTCHD3 PTPN7 RAB3IL1 RASD1 RBM48 RDM1 RINT1 RNF6 ROBO3 RUSC1 RXRB SAXO4 SFI1 SH3KBP1 SHISA6 SIRPA SLC25A48 SMG9 SNRNP35 SORBS3 SPMIP2 SPMIP6 SPRY1 SYT6 TBC1D22B TCP10L TFIP11 TFPT TIMM44 TLE5 TMEM100 TNNI1 TP53BP2 TRIM14 TRIM29 TSEN54 TSGA10IP TSHZ2 TXLNA USP15 USP2 UTP14C VPS52 YJU2 ZBTB4 ZC2HC1C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF436 ZNF474 ZNF552 ZNF648 ZNF655 ZNF688 ZNF835 ZSWIM3
Entrez ID		6924	284001
HPRD ID		02873	14150
Ensembl ID		ENSG00000011007	ENSG00000176155
Uniprot IDs		Q14241	A0A590UJT6 Q2TAC2
PDB IDs		4HFX 6ZUZ 8OEV 8OEW 8OF0
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cytoskeleton Organization Identical Protein Binding Regulation Of Organelle Organization Regulation Of Microtubule-based Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Negative Regulation Of RNA Metabolic Process Regulation Of Cytoskeleton Organization Microtubule-based Process Centriole Replication Regulation Of Centriole Replication Regulation Of Protein Localization To Synapse Nuclear Pore Localization Regulation Of Receptor Localization To Synapse Centriole Assembly Negative Regulation Of Microtubule Depolymerization Negative Regulation Of Metabolic Process Ubiquitin Protein Ligase Activity Microtubule Organizing Center Organization Negative Regulation Of Supramolecular Fiber Organization Protein Ubiquitination Negative Regulation Of Centriole Replication Regulation Of Microtubule Depolymerization Cytoplasm Negative Regulation Of Microtubule Polymerization Or Depolymerization Protein Modification By Small Protein Conjugation Negative Regulation Of Macromolecule Metabolic Process Ubiquitin Protein Ligase Binding Regulation Of Centrosome Duplication Protein Binding Negative Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Dorsal/ventral Axis Specification Trophoblast Giant Cell Differentiation Protein Localization To Microtubule Cytoskeleton XY Body Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cul5-RING Ubiquitin Ligase Complex Regulation Of RNA Metabolic Process	Protein Binding Spliceosomal Complex Nucleus Cytoskeleton MRNA Splicing, Via Spliceosome RNA Splicing Axonemal A Tubule Inner Sheath RNA Splicing, Via Transesterification Reactions
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