ELOA and CNTROB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ELOA	CNTROB
Description		elongin A	centrobin, centriole duplication and spindle assembly protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Elongin Complex Site Of DNA Damage	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Ciliary Basal Body
	Molecular Function	Protein Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Transcription Elongation By RNA Polymerase II	Centriole Replication Centrosome Separation Cell Division Regulation Of Cilium Assembly Mitotic Cytokinetic Process
Pathways		Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		58 interacting genes: AXIN2 BACH2 BRCA1 CBY2 CCDC57 CDR2L CEP57L1 CEP70 CNTROB CUL5 DLGAP1-AS2 ELOB ERCC6 EVI5 FAM9B FCHO1 FXR1 GMCL1 GOLGA6A GRIPAP1 HIVEP1 HOMEZ JAKMIP2 KANK2 KLHL2 KRT40 KRTAP10-3 KXD1 LMNA LZTS1 MCC MDFI MED21 MID1 MID2 NAB2 NACC1 NAF1 NFKBID NINL OGT PER2 PLK4 PPFIA1 PRDM6 PRMT5 RABEP1 RAD54B RAP1A REXO1 RNF10 SIRPA SPECC1L TNIP1 TP53BP2 TRIM37 TRIM54 ZNF792	20 interacting genes: APTX COASY CWF19L2 DAPK1 DUSP29 ELOA EPM2AIP1 GSK3A LYST MCRS1 PELI1 PNKP RAD23A RSPH14 SMARCA2 SYT6 TCEA2 TSC1 TSHZ2 TTC23
Entrez ID		6924	116840
HPRD ID		02873	13991
Ensembl ID		ENSG00000011007	ENSG00000170037
Uniprot IDs		Q14241	Q8N137
PDB IDs		4HFX 6ZUZ 8OEV 8OEW 8OF0
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cytoskeleton Organization Identical Protein Binding Regulation Of Organelle Organization Regulation Of Microtubule-based Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Negative Regulation Of RNA Metabolic Process Regulation Of Cytoskeleton Organization Microtubule-based Process Centriole Replication Regulation Of Centriole Replication Regulation Of Protein Localization To Synapse Nuclear Pore Localization Regulation Of Receptor Localization To Synapse Centriole Assembly Negative Regulation Of Microtubule Depolymerization Negative Regulation Of Metabolic Process Ubiquitin Protein Ligase Activity Microtubule Organizing Center Organization Negative Regulation Of Supramolecular Fiber Organization Protein Ubiquitination Negative Regulation Of Centriole Replication Regulation Of Microtubule Depolymerization Cytoplasm Negative Regulation Of Microtubule Polymerization Or Depolymerization Protein Modification By Small Protein Conjugation Negative Regulation Of Macromolecule Metabolic Process Ubiquitin Protein Ligase Binding Regulation Of Centrosome Duplication Protein Binding Negative Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Dorsal/ventral Axis Specification Trophoblast Giant Cell Differentiation Protein Localization To Microtubule Cytoskeleton XY Body Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cul5-RING Ubiquitin Ligase Complex Regulation Of RNA Metabolic Process	Polynucleotide 3'-phosphatase Activity DNA Metabolic Process DNA Repair Positive Regulation Of DNA Repair Damaged DNA Binding Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of TOR Signaling Regulation Of DNA Repair Positive Regulation Of Double-strand Break Repair DNA Damage Response Positive Regulation Of DNA Metabolic Process Cellular Response To Stress DAPK1-calmodulin Complex Macromolecule Metabolic Process Positive Regulation Of Autophagic Cell Death Negative Regulation Of UDP-glucose Catabolic Process Regulation Of Glycogen Metabolic Process Regulation Of TOR Signaling Regulation Of Glycogen Biosynthetic Process Response To Insulin Regulation Of Double-strand Break Repair Memory T Cell Differentiation DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Pantetheine-phosphate Adenylyltransferase Activity
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