SERTAD1 and HIVEP1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		SERTAD1	HIVEP1
Description		SERTA domain containing 1	HIVEP zinc finger 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Sarcoplasm	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Nuclear Body
	Molecular Function	Transcription Coactivator Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Population Proliferation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II BMP Signaling Pathway Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Monocyte percentage of white cells ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)	Adult body size ( 32376654) Alcohol and nicotine co-dependence ( 22488850) Asthma ( 32296059) Body mass index ( 25673413 28892062 29273807) Chronotype ( 30696823) Feeling worry ( 29500382) Figural/spatial cognitive ability ( 31620175) General risk tolerance (MTAG) ( 30643258) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483) Monocyte count ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Red blood cell count ( 32888494) Takayasu arteritis ( 25604533)
Interacting Genes		56 interacting genes: ADCY1 AIRIM ASB8 ATG12 ATXN7L3 BANF2 CCND2 CDK4 CDKN2A CHAF1A CHURC1 CIB3 CINP CKS1B COPB1 CREBBP DENND4A EGLN3 ELOC EP300 FAAP20 FAH FNDC11 FXR1 GLYCTK HIVEP1 HSPB1 KAT2B KLC4 KLHL42 MVP P4HA3 PATE1 PBX4 PICK1 PIH1D2 POT1 PRDM4 PSORS1C2 RBX1 RCHY1 ROPN1 SEC14L4 SETD7 SFI1 SMAD3 SPEN SSX7 STAT5B SUPT7L TGM2 TLR4 TRIM28 TSC1 XIAP ZNF410	72 interacting genes: ALDOB APH1A APTX ASGR1 ATXN1 ATXN1L BANP BHLHE40 BNIP3 BRCA1 CACNA1A CCNK CDC37 CLK1 CREB1 CREBBP DNAJA1 ELOA EMG1 FXR1 FXR2 GAA GSDMB HPD HSPA1A IGFN1 IMMT KDF1 MAGED1 MAPK14 MAPK8 MIEN1 MTMR3 NINJ1 NLGN3 NRF1 NUCB1 OGT OTX1 PLEKHB2 POGZ POU2F1 POU6F2 PRKAR1A PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RAB1A RBM47 RBPMS RIDA RNF186 ROR2 SDCBP SERTAD1 SH3KBP1 SMAD3 SNX4 SOCS3 SOX10 SP4 SRPK2 STAT3 TENT5B TMEM176A VCF2 VEZF1 ZC3H10 ZFHX3
Entrez ID		29950	3096
HPRD ID		15326	01925
Ensembl ID		ENSG00000197019	ENSG00000095951
Uniprot IDs		Q53GC0 Q9UHV2	A0A0D9SFF3 A0AAQ5BHS1 H7BYU7 P15822
PDB IDs			1BBO 3ZNF 4ZNF
Enriched GO Terms of Interacting Partners?		N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Macromolecule Biosynthetic Process P53 Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Stress RNA Polymerase II-specific DNA-binding Transcription Factor Binding Peptidyl-lysine Acetylation N-terminal Protein Amino Acid Acetylation Histone H3K27 Acetyltransferase Activity Regulation Of DNA Repair Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Protein Localization To Nucleus Protein Binding Cellular Response To Stress Cyclin D2-CDK4 Complex Acetyltransferase Activity Histone H3K18 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Nucleus Protein Modification Process DNA Damage Response Canonical NF-kappaB Signal Transduction Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Histone Acetyltransferase Complex Transcription Coregulator Activity SAGA Complex Protein-lysine-acetyltransferase Activity Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Protein Stabilization Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Chromatin Regulation Of Protein Localization To Nucleus Chromatin Binding Histone Acetyltransferase Activity L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Chromo Shadow Domain Binding Protein Acetylation Cellular Response To Nutrient Levels Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Positive Regulation Of Protein Import Into Nucleus	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Developmental Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of MRNA Stability Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Stability Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Differentiation Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Chromatin Regulation Of Developmental Process Regulation Of Biological Quality Transcription By RNA Polymerase II Pyroptotic Inflammatory Response Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Post-transcriptional Regulation Of Gene Expression Enzyme Binding Positive Regulation Of Multicellular Organismal Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Nucleus Regulation Of Multicellular Organismal Process Rhythmic Process DNA-binding Transcription Factor Activity POZ Domain Binding Regulation Of Circadian Rhythm Positive Regulation Of MRNA Catabolic Process Regulation Of RNA Splicing MRF Binding C3HC4-type RING Finger Domain Binding Regulation Of MiRNA-mediated Gene Silencing
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