BTBD6 and GRSF1

Number of citations of the paper that reports this interaction (PubMedID 32645484)
0

Data Source:
BioGRID (two hybrid)

		BTBD6	GRSF1
Description		BTB domain containing 6	G-rich RNA sequence binding factor 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Ribonucleoprotein Granule Mitochondrial Nucleoid Ribonucleoprotein Complex
	Molecular Function	Protein Binding	G-quadruplex RNA Binding Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Neurogenesis	Mitochondrial RNA Catabolic Process Positive Regulation Of Mitochondrial RNA Catabolic Process MRNA Processing TRNA Processing Anterior/posterior Pattern Specification Morphogenesis Of Embryonic Epithelium Regulation Of RNA Splicing
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Viral mRNA Translation Mitochondrial RNA degradation
Drugs
Diseases
GWAS			Type 2 diabetes ( 30718926)
Interacting Genes		10 interacting genes: BTBD3 CUL3 DAXX FXR1 GRSF1 NFKBIB NME7 NTAQ1 PAXIP1 TCEA2	55 interacting genes: AUP1 BTBD6 CNRIP1 COMMD1 CYC1 DACT1 EIF1B ERO1A FADS2 FNTA FYN GSE1 GTF2E2 HCFC2 HIVEP3 ISYNA1 MAP6 MIR1-2 MIR106B MIR18B MIR200B MIR200C MIR205 MIR25 MIR31 MIR451A MIR9-1 MIR9-2 MIR92A1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I NEUROD2 NOP53 NUP153 NUP93 OGT PIN1 PPIA PRNP PSMD10 RAB3A RING1 SLC25A21-AS1 UBE3C VPS11 ZNF3
Entrez ID		90135	2926
HPRD ID		12540	07276
Ensembl ID		ENSG00000184887	ENSG00000132463
Uniprot IDs		A0A384NYR4 A0A8C8KHP4 Q96KE9	Q12849
PDB IDs		2VKP	2LMI 4QU6 4QU7
Enriched GO Terms of Interacting Partners?		Ribonucleoprotein Granule Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification Molecular Condensate Scaffold Activity Nucleic Acid Metabolic Process Transcription Elongation By RNA Polymerase II DNA-templated Transcription Elongation Neuron Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Regulation Of RNA Metabolic Process Nucleus Cellular Response To Diamide Nucleobase-containing Compound Catabolic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Rho Protein Signal Transduction Trophectodermal Cellular Morphogenesis Liver Morphogenesis Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Mitochondrial RNA Catabolic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Protein Catabolic Process At Postsynapse Positive Regulation Of Protein Ubiquitination Chorion Development Positive Regulation Of RNA Metabolic Process	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MRNA 3'-UTR Binding Negative Regulation Of Translation MRNA Destabilization Negative Regulation Of Protein Metabolic Process RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cell Motility Negative Regulation Of Signal Transduction Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Locomotion Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Protein Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Translation Negative Regulation Of Cell Migration Regulation Of MRNA Stability Positive Regulation Of Catabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of RNA Stability Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Migration Regulation Of Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development
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