BTBD6 and BTBD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BTBD6	BTBD3
Description		BTB domain containing 6	BTB domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Neurogenesis	Nervous System Development Cerebral Cortex Development Neurogenesis Dendrite Morphogenesis
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Benign prostatic hyperplasia ( 30988330) Cardiac hypertrophy ( 21348951) Cognitive decline rate in late mild cognitive impairment ( 26252872) Diastolic blood pressure ( 30224653) Hearing function ( 25060954) Intraocular pressure ( 29785010) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Serum metabolite levels ( 33031748) Serum metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		10 interacting genes: BTBD3 CUL3 DAXX FXR1 GRSF1 NFKBIB NME7 NTAQ1 PAXIP1 TCEA2	10 interacting genes: BTBD6 CDC37 CUL3 GORASP2 MEOX2 PLXNB3 RNF4 SUMO1 TEPSIN UBE2I
Entrez ID		90135	22903
HPRD ID		12540	12538
Ensembl ID		ENSG00000184887	ENSG00000132640
Uniprot IDs		A0A384NYR4 A0A8C8KHP4 Q96KE9	B4DK27 B4DRI6 Q9Y2F9
PDB IDs		2VKP
Enriched GO Terms of Interacting Partners?		Ribonucleoprotein Granule Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification Molecular Condensate Scaffold Activity Nucleic Acid Metabolic Process Transcription Elongation By RNA Polymerase II DNA-templated Transcription Elongation Neuron Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Regulation Of RNA Metabolic Process Nucleus Cellular Response To Diamide Nucleobase-containing Compound Catabolic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Rho Protein Signal Transduction Trophectodermal Cellular Morphogenesis Liver Morphogenesis Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Mitochondrial RNA Catabolic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Protein Catabolic Process At Postsynapse Positive Regulation Of Protein Ubiquitination Chorion Development Positive Regulation Of RNA Metabolic Process	Small Protein Activating Enzyme Binding PML Body Transcription Factor Binding Presynaptic Cytosol Postsynaptic Cytosol Roof Of Mouth Development Post-translational Protein Modification Nuclear Body Protein Modification By Small Protein Conjugation Protein Autoubiquitination Protein Sumoylation SUMO Conjugating Enzyme Activity Nuclear Pore Regulation Of Protein Stability Trophectodermal Cellular Morphogenesis Liver Morphogenesis HSP90-CDC37 Chaperone Complex Coated Vesicle Membrane Rho GDP-dissociation Inhibitor Binding Regulation Of Kinetochore Assembly Protein K48-linked Ubiquitination RING-like Zinc Finger Domain Binding Protein Localization To Nuclear Pore Regulation Protein Catabolic Process At Postsynapse
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