TACC1 and SH2D4A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TACC1	SH2D4A
Gene Name		transforming, acidic coiled-coil containing protein 1	SH2 domain containing 4A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Microtubule Cytoskeleton Intermediate Filament Cytoskeleton	Cytoplasm
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding Phosphatase Binding
	Biological Process	Microtubule Cytoskeleton Organization Cell Cycle Cell Proliferation Cerebral Cortex Development Neurogenesis Interkinetic Nuclear Migration Regulation Of Microtubule-based Process Cell Division	Negative Regulation Of Phosphatase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: AURKA AURKB BTRC CKAP5 HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 PRKRIR SH2D4A SNRPG STX5 TDRD7 YEATS4	43 interactors: ALAS1 CASK CCDC172 CDR2 CEP70 CEP76 DBNL FSD2 GOLGA2 GRB2 HCLS1 HMBOX1 IKZF1 KRT40 LDOC1 LZTS2 MAGEA11 MAGEA6 MTUS2 NECAB2 NINL NUTM1 PDE4DIP PNMA1 PPP1CB PSTPIP1 RINT1 SH3GL1 SKAP1 SORBS2 SORBS3 SPAG5 STAM2 STX11 TACC1 TFIP11 TRAF2 TRIM23 TRIM27 UBXN11 USHBP1 VPS52 ZBTB16
Entrez ID		6867	63898
HPRD ID		10391	08340
Ensembl ID		ENSG00000147526	ENSG00000104611
Uniprot IDs		G8JLK4 O75410 Q5HYH0	Q9H788
PDB IDs
Enriched GO Terms of Interacting Partners?		Spindle Stabilization Mitotic Cell Cycle Process Histone Modification Mitotic Cell Cycle Negative Regulation Of Protein Binding Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Histone-serine Phosphorylation Chromatin Modification Cell Cycle Process Negative Regulation Of Binding Mitotic Nuclear Division G2/M Transition Of Mitotic Cell Cycle Chromatin Organization Spindle Organization Regulation Of Protein Stability Regulation Of Protein Binding Cell Cycle Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Posttranscriptional Regulation Of Gene Expression Histone Phosphorylation Negative Regulation Of Microtubule Depolymerization Mitotic Spindle Organization Positive Regulation Of Protein Catabolic Process Chromosome Organization Organelle Organization Negative Regulation Of Microtubule Polymerization Or Depolymerization Histone H4 Acetylation Anterior/posterior Pattern Specification Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cytokinesis Proteasomal Protein Catabolic Process Regulation Of Binding Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Neural Plate Formation Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Spindle Checkpoint Positive Regulation Of Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Microtubule Polymerization Or Depolymerization Cell Proliferation Golgi Organization Spindle Assembly Spindle Assembly Involved In Female Meiosis I Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Microtubule-based Process Diencephalon Development Centrosome Organization	Cell Cycle Positive Regulation Of NK T Cell Differentiation G2/M Transition Of Mitotic Cell Cycle Organelle Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Granulocyte Differentiation Mitotic Cell Cycle Immune System Process Positive Regulation Of Cytoskeleton Organization Regulation Of Cell Adhesion Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Cell Division Mitotic Cell Cycle Process Positive Regulation Of Cell-cell Adhesion Protein Complex Assembly Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Calcium Ion Import Actin Filament Organization Regulation Of T Cell Activation Cytoskeleton Organization Positive Regulation Of Cell Activation Protein K63-linked Ubiquitination Protein Trimerization Cellular Protein Complex Assembly Positive Regulation Of Immune System Process Regulation Of Organelle Organization Regulation Of Microtubule-based Process Positive Regulation Of Neutrophil Differentiation Spliceosomal Complex Disassembly Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Regulation Of Actin Cytoskeleton Organization Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Positive Regulation Of Alpha-beta T Cell Differentiation Regulation Of Immune System Process Regulation Of Myeloid Cell Differentiation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Actin Filament Polymerization Positive Regulation Of Cellular Metabolic Process Regulation Of Lymphocyte Activation Negative Regulation Of ERBB Signaling Pathway Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Cellular Localization Cell Cycle Process Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length
Tagcloud ?		acidic additionally amplification clinicopathological coil coiled correlation cytoplasmic dysregulation fda fish gc her2 immunohistochemistry indicator lymph maybe node occurs positive prognostic resected stage synergistic thought tnm transforming unclear valuable
Tagcloud (Difference) ?		acidic additionally amplification clinicopathological coil coiled correlation cytoplasmic dysregulation fda fish gc her2 immunohistochemistry indicator lymph maybe node occurs positive prognostic resected stage synergistic thought tnm transforming unclear valuable
Tagcloud (Intersection) ?