TACC1 and SNRPG

Number of citations of the paper that reports this interaction (PubMedID 12165861)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		TACC1	SNRPG
Description		transforming acidic coiled-coil containing protein 1	small nuclear ribonucleoprotein polypeptide G
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Membrane Midbody	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U2-type Spliceosomal Complex U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome SMN-Sm Protein Complex P Granule U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Ribonucleoprotein Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Nuclear Receptor Binding Nuclear Estrogen Receptor Binding Nuclear Glucocorticoid Receptor Binding Nuclear Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Nuclear Retinoid X Receptor Binding Nuclear Thyroid Hormone Receptor Binding	RNA Binding Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Nuclear Migration Cerebral Cortex Development Positive Regulation Of DNA-templated Transcription Cell Division	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing 7-methylguanosine Cap Hypermethylation U2-type Prespliceosome Assembly
Pathways			SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Chronic mountain sickness ( 31417607) Midgestational circulating levels of PBDEs ( 28235828)	Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)
Interacting Genes		20 interacting genes: AURKA AURKB BTRC ERCC4 FAM50B HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 SH2D4A SNRPG STX5 TDRD7 THAP12 THRA YEATS4 ZFHX3 ZNF48	22 interacting genes: CEBPA CEP126 COPS6 CRMP1 DDIT4L DDX20 ERG28 FHL3 GDF9 GEMIN5 GEMIN6 IL7R LSM3 PEA15 RBPMS SMN2 SNRPD3 SNRPE SNRPF TACC1 TCL1B TLE1
Entrez ID		6867	6637
HPRD ID		10391	04646
Ensembl ID		ENSG00000147526	ENSG00000143977
Uniprot IDs		B7Z3G3 E5RFM9 E7ET87 E7EVI4 O75410	C9JVQ0 F5H013 P62308 Q49AN9
PDB IDs			3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6V4X 6Y53 6Y5Q 7A5P 7ABG 7ABI 7B0Y 7DVQ 7EVO 7QTT 7VPX 7W59 7W5A 7W5B 8C6J 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7Q 8Q7V 8Q7W 8Q7X 8Q91 8QO9 8QZS 8R08 8R09 8R0A 8R0B 8R7N 8RC0 8RM5 8RO2 8Y6O 8Y7E 9FMD 9GBW 9GC0 9GCL
Enriched GO Terms of Interacting Partners?		Spliceosomal Tri-snRNP Complex Chromosome Passenger Complex Nucleoplasm Nucleus Regulation Of DNA Metabolic Process Cellular Response To UV Regulation Of Microtubule-based Process U2-type Prespliceosome P Granule Cellular Response To Light Stimulus Microtubule Cytoskeleton Organization Involved In Mitosis U12-type Spliceosomal Complex Regulation Of Signal Transduction By P53 Class Mediator Spindle Midzone Protein Serine/threonine/tyrosine Kinase Activity Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Component Organization Response To UV Cellular Response To Radiation Regulation Of Cell Division Peptidyl-lysine Glutarylation Histone Glutaryltransferase Activity Histone Succinyltransferase Activity Regulation Of Protein Stability Peptide Glutaryltransferase Activity U4/U6 X U5 Tri-snRNP Complex Spindle Microtubule Mitotic Spindle Pole Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Negative Regulation Of Nucleobase-containing Compound Metabolic Process Midbody Negative Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Locomotor Rhythm Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Nucleotide-excision Repair Involved In Interstrand Cross-link Repair Regulation Of Organelle Organization Regulation Of Centrosome Cycle Regulation Of DNA Repair Chromatin Organization Histone H3K9 Acetyltransferase Activity Protein Destabilization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity U2-type Precatalytic Spliceosome Cell Cycle G2/M Phase Transition Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly	SMN-Sm Protein Complex Spliceosomal SnRNP Assembly SMN Complex Gemini Of Cajal Bodies Spliceosomal Complex Assembly Protein-RNA Complex Assembly RNA Splicing, Via Transesterification Reactions RNA Splicing PICln-Sm Protein Complex MRNA Processing U7 SnRNP 7-methylguanosine Cap Hypermethylation MRNA Splicing, Via Spliceosome U4/U6 X U5 Tri-snRNP Complex U4 SnRNP Methylosome U2-type Precatalytic Spliceosome MRNA Metabolic Process RNA Processing Small Nuclear Ribonucleoprotein Complex Precatalytic Spliceosome U1 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex Catalytic Step 2 Spliceosome U2 SnRNP U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome RNA Metabolic Process Spliceosomal Complex Cellular Component Assembly Nucleoplasm Nuclear Body Protein-containing Complex Assembly RNA Methylation Cytosol Protein-containing Complex Organization Telomerase Holoenzyme Complex Macromolecule Methylation RNA Binding Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Modification RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding SMN-Gemin2 Complex Cytoplasm Ribonucleoprotein Complex DNA-binding Transcription Factor Binding Midbody
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