TACC1 and PRKRIR

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TACC1	PRKRIR
Gene Name		transforming, acidic coiled-coil containing protein 1	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Microtubule Cytoskeleton Intermediate Filament Cytoskeleton	Nucleus
	Molecular Function	Protein Binding Protein Domain Specific Binding	DNA Binding Metal Ion Binding Protein Dimerization Activity
	Biological Process	Microtubule Cytoskeleton Organization Cell Cycle Cell Proliferation Cerebral Cortex Development Neurogenesis Interkinetic Nuclear Migration Regulation Of Microtubule-based Process Cell Division	Response To Stress Signal Transduction Negative Regulation Of Cell Proliferation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: AURKA AURKB BTRC CKAP5 HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 PRKRIR SH2D4A SNRPG STX5 TDRD7 YEATS4	7 interactors: DDX58 DNAJC3 EIF2AK2 EIF2S1 STK4 TACC1 TP53
Entrez ID		6867	5612
HPRD ID		10391	09567
Ensembl ID		ENSG00000147526	ENSG00000137492
Uniprot IDs		G8JLK4 O75410 Q5HYH0	O43422
PDB IDs
Enriched GO Terms of Interacting Partners?		Spindle Stabilization Mitotic Cell Cycle Process Histone Modification Mitotic Cell Cycle Negative Regulation Of Protein Binding Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Histone-serine Phosphorylation Chromatin Modification Cell Cycle Process Negative Regulation Of Binding Mitotic Nuclear Division G2/M Transition Of Mitotic Cell Cycle Chromatin Organization Spindle Organization Regulation Of Protein Stability Regulation Of Protein Binding Cell Cycle Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Posttranscriptional Regulation Of Gene Expression Histone Phosphorylation Negative Regulation Of Microtubule Depolymerization Mitotic Spindle Organization Positive Regulation Of Protein Catabolic Process Chromosome Organization Organelle Organization Negative Regulation Of Microtubule Polymerization Or Depolymerization Histone H4 Acetylation Anterior/posterior Pattern Specification Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cytokinesis Proteasomal Protein Catabolic Process Regulation Of Binding Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Neural Plate Formation Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Spindle Checkpoint Positive Regulation Of Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Microtubule Polymerization Or Depolymerization Cell Proliferation Golgi Organization Spindle Assembly Spindle Assembly Involved In Female Meiosis I Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Microtubule-based Process Diencephalon Development Centrosome Organization	ER-nucleus Signaling Pathway Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein Regulation Of Translational Initiation In Response To Stress Cellular Response To Topologically Incorrect Protein Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Response To Unfolded Protein Positive Regulation Of Kinase Activity Positive Regulation Of Protein Metabolic Process Regulation Of Translation In Response To Stress Regulation Of Phosphorylation Positive Regulation Of Transferase Activity Defense Response To Virus Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorus Metabolic Process Protein Autophosphorylation Regulation Of Protein Kinase Activity Response To Biotic Stimulus Regulation Of Kinase Activity Response To Virus Positive Regulation Of Metabolic Process Regulation Of Cellular Protein Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Immune System Process Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Translational Initiation Response To Organic Substance Regulation Of Defense Response To Virus Evasion Or Tolerance By Virus Of Host Immune Response Viral Process Regulation Of Apoptotic Process Regulation Of Stem Cell Proliferation Cellular Response To Stress Positive Regulation Of Catalytic Activity Regulation Of Cell Death Negative Regulation Of Macromitophagy Regulation Of Hematopoietic Stem Cell Differentiation Oligodendrocyte Apoptotic Process Signal Transduction Negative Regulation Of Cell Proliferation Negative Regulation Of Helicase Activity RIG-I Signaling Pathway
Tagcloud ?		acidic additionally amplification clinicopathological coil coiled correlation cytoplasmic dysregulation fda fish gc her2 immunohistochemistry indicator lymph maybe node occurs positive prognostic resected stage synergistic thought tnm transforming unclear valuable
Tagcloud (Difference) ?		acidic additionally amplification clinicopathological coil coiled correlation cytoplasmic dysregulation fda fish gc her2 immunohistochemistry indicator lymph maybe node occurs positive prognostic resected stage synergistic thought tnm transforming unclear valuable
Tagcloud (Intersection) ?