TAC1 and TAC4

Number of citations of the paper that reports this interaction (PMID 11786503)
7

Data Source:
BioGRID (pull down)

		TAC1	TAC4
Gene Name		tachykinin, precursor 1	tachykinin 4 (hemokinin)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Axon Neuronal Cell Body	Extracellular Region
	Molecular Function	Protein Binding Substance P Receptor Binding	Receptor Binding
	Biological Process	Positive Regulation Of Acute Inflammatory Response Inflammatory Response Positive Regulation Of Cytosolic Calcium Ion Concentration Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Cell-cell Signaling Synaptic Transmission Insemination Long-term Memory Regulation Of Blood Pressure Associative Learning Detection Of Abiotic Stimulus Response To Hormone Negative Regulation Of Heart Rate Positive Regulation Of Epithelial Cell Migration Sensory Perception Of Pain Positive Regulation Of Synaptic Transmission, Cholinergic Positive Regulation Of Synaptic Transmission, GABAergic Response To Lipopolysaccharide Positive Regulation Of Renal Sodium Excretion Response To Morphine Positive Regulation Of Action Potential Positive Regulation Of Ossification Positive Regulation Of Saliva Secretion Response To Pain Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Corticosterone Secretion	Tachykinin Receptor Signaling Pathway Regulation Of Blood Pressure Positive Regulation Of Saliva Secretion
Pathways		G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Tachykinin receptors bind tachykinins Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Adverse response to radiation therapy ( 23719583) Response to platinum-based agents ( 22020760)
Protein-Protein Interactions		12 interactors: ARHGEF40 BAG6 CENPB FN1 MEP1A PREP TAC4 TACR1 TACR2 TACR3 TFF2 XRCC6	4 interactors: TAC1 TACR1 TACR2 TACR3
Entrez ID		6863	255061
HPRD ID		08876	09701
Ensembl ID		ENSG00000006128	ENSG00000176358
Uniprot IDs		P20366 Q9Y494	Q86UU9
PDB IDs		2B19 2KS9 2KSA 2KSB
Enriched GO Terms of Interacting Partners?		Tachykinin Receptor Signaling Pathway Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Saliva Secretion Regulation Of Smooth Muscle Contraction Operant Conditioning Regulation Of Saliva Secretion Hyperosmotic Salinity Response Neuropeptide Signaling Pathway Blood Circulation Positive Regulation Of Digestive System Process Positive Regulation Of Vascular Permeability Regulation Of Muscle Contraction Hyperosmotic Response Regulation Of Blood Pressure Regulation Of Vascular Permeability Response To Salt Stress Positive Regulation Of Blood Pressure Response To Morphine Regulation Of Secretion Response To Electrical Stimulus Excretion Smooth Muscle Contraction Positive Regulation Of Secretion Positive Regulation Of Acetylcholine Secretion, Neurotransmission Acute Inflammatory Response Response To Osmotic Stress Response To Ammonium Ion Positive Regulation Of Synaptic Transmission Cellular Hyperosmotic Salinity Response Smooth Muscle Contraction Involved In Micturition Intestine Smooth Muscle Contraction Negative Regulation Of Luteinizing Hormone Secretion Angiotensin-mediated Drinking Behavior Response To Abiotic Stimulus Digestion Response To Estradiol G-protein Coupled Receptor Signaling Pathway Regulation Of Acetylcholine Secretion, Neurotransmission Calcium-independent Cell-matrix Adhesion Learning Positive Regulation Of Synaptic Transmission, Cholinergic Response To Alkaloid Synaptic Transmission Prolactin Secretion Cellular Response To X-ray Negative Regulation Of Gastric Acid Secretion Negative Regulation Of Gonadotropin Secretion Micturition Response To Ozone	Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Smooth Muscle Contraction Response To Morphine Blood Circulation Regulation Of Smooth Muscle Contraction Positive Regulation Of Synaptic Transmission, Cholinergic Positive Regulation Of Saliva Secretion Response To Ammonium Ion Operant Conditioning Regulation Of Synaptic Transmission, Cholinergic Regulation Of Saliva Secretion Synaptic Transmission Positive Regulation Of Synaptic Transmission Positive Regulation Of Action Potential Learning Response To Alkaloid Regulation Of Muscle Contraction Positive Regulation Of Digestive System Process Positive Regulation Of Vascular Permeability Positive Regulation Of Renal Sodium Excretion Regulation Of Blood Pressure Positive Regulation Of Synaptic Transmission, GABAergic Cell-cell Signaling Insemination Regulation Of Renal Sodium Excretion Response To Abiotic Stimulus Copulation Regulation Of Hormone Secretion Learning Or Memory Regulation Of Excretion G-protein Coupled Receptor Signaling Pathway Cognition Regulation Of Synaptic Transmission Regulation Of Vascular Permeability Positive Regulation Of Secretion Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of Blood Pressure Response To Pain Response To Electrical Stimulus Positive Regulation Of Stress Fiber Assembly Long-term Memory Excretion Positive Regulation Of Actin Filament Bundle Assembly Single-organism Behavior Mating Smooth Muscle Contraction Regulation Of Stress Fiber Assembly Regulation Of Heart Rate
Tagcloud ?		1st affymetrix barcoding capn6 comprehensively corneal corneas dystrophies dystrophy fecd fecd4 fuchs genechip hcenc hist1h3a hist1h4e hspa2 hybridized itgbl1 nalcn partek polymorphous ppcd ppcd1 prex2 scientists suite tmod1 xecd
Tagcloud (Difference) ?		1st affymetrix barcoding capn6 comprehensively corneal corneas dystrophies dystrophy fecd fecd4 fuchs genechip hcenc hist1h3a hist1h4e hspa2 hybridized itgbl1 nalcn partek polymorphous ppcd ppcd1 prex2 scientists suite tmod1 xecd
Tagcloud (Intersection) ?