TAC4 and TACR2

Number of citations of the paper that reports this interaction (PMID 11786503)
7

Data Source:
HPRD (in vivo, in vitro)

		TAC4	TACR2
Gene Name		tachykinin 4 (hemokinin)	tachykinin receptor 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Receptor Binding	Tachykinin Receptor Activity Protein Binding Substance K Receptor Activity
	Biological Process	Tachykinin Receptor Signaling Pathway Regulation Of Blood Pressure Positive Regulation Of Saliva Secretion	Muscle Contraction Tachykinin Receptor Signaling Pathway Excretion Positive Regulation Of Acetylcholine Secretion, Neurotransmission Intestine Smooth Muscle Contraction Negative Regulation Of Luteinizing Hormone Secretion Operant Conditioning Positive Regulation Of Vascular Permeability Response To Electrical Stimulus Prolactin Secretion Positive Regulation Of Uterine Smooth Muscle Contraction
Pathways			G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Tachykinin receptors bind tachykinins Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: TAC1 TACR1 TACR2 TACR3	4 interactors: GPRASP1 TAC1 TAC3 TAC4
Entrez ID		255061	6865
HPRD ID		09701	01207
Ensembl ID		ENSG00000176358	ENSG00000075073
Uniprot IDs		Q86UU9	P21452
PDB IDs
Enriched GO Terms of Interacting Partners?		Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Smooth Muscle Contraction Response To Morphine Blood Circulation Regulation Of Smooth Muscle Contraction Positive Regulation Of Synaptic Transmission, Cholinergic Positive Regulation Of Saliva Secretion Response To Ammonium Ion Operant Conditioning Regulation Of Synaptic Transmission, Cholinergic Regulation Of Saliva Secretion Synaptic Transmission Positive Regulation Of Synaptic Transmission Positive Regulation Of Action Potential Learning Response To Alkaloid Regulation Of Muscle Contraction Positive Regulation Of Digestive System Process Positive Regulation Of Vascular Permeability Positive Regulation Of Renal Sodium Excretion Regulation Of Blood Pressure Positive Regulation Of Synaptic Transmission, GABAergic Cell-cell Signaling Insemination Regulation Of Renal Sodium Excretion Response To Abiotic Stimulus Copulation Regulation Of Hormone Secretion Learning Or Memory Regulation Of Excretion G-protein Coupled Receptor Signaling Pathway Cognition Regulation Of Synaptic Transmission Regulation Of Vascular Permeability Positive Regulation Of Secretion Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of Blood Pressure Response To Pain Response To Electrical Stimulus Positive Regulation Of Stress Fiber Assembly Long-term Memory Excretion Positive Regulation Of Actin Filament Bundle Assembly Single-organism Behavior Mating Smooth Muscle Contraction Regulation Of Stress Fiber Assembly Regulation Of Heart Rate	Tachykinin Receptor Signaling Pathway Positive Regulation Of Saliva Secretion Regulation Of Saliva Secretion Positive Regulation Of Digestive System Process Neuropeptide Signaling Pathway G-protein Coupled Receptor Catabolic Process Positive Regulation Of Corticosterone Secretion Regulation Of Blood Pressure G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Synaptic Transmission, Cholinergic Regulation Of Corticosterone Secretion Blood Circulation Regulation Of Synaptic Transmission, Cholinergic Positive Regulation Of Secretion Positive Regulation Of Action Potential Negative Regulation Of Heart Rate Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Synaptic Transmission, GABAergic Insemination Receptor Catabolic Process Regulation Of Renal Sodium Excretion Copulation Negative Regulation Of Heart Contraction Regulation Of Excretion Regulation Of Secretion Positive Regulation Of Acute Inflammatory Response Endosome To Lysosome Transport Positive Regulation Of Transport Regulation Of Synaptic Transmission, GABAergic Response To Pain Response To Morphine Positive Regulation Of Stress Fiber Assembly Lysosomal Transport Long-term Memory Positive Regulation Of Actin Filament Bundle Assembly Cell Surface Receptor Signaling Pathway Mating Positive Regulation Of Lipid Transport Regulation Of Stress Fiber Assembly Regulation Of Acute Inflammatory Response Regulation Of Heart Rate Vacuolar Transport Positive Regulation Of Epithelial Cell Migration Receptor Metabolic Process Associative Learning Multicellular Organismal Response To Stress Sensory Perception Of Pain Response To Ammonium Ion Regulation Of Lipid Transport Positive Regulation Of Inflammatory Response
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