TAC1 and TACR3

Number of citations of the paper that reports this interaction (PMID 9272936)
10

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		TAC1	TACR3
Gene Name		tachykinin, precursor 1	tachykinin receptor 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Axon Neuronal Cell Body	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Dendrite Membrane Neuronal Cell Body Membrane
	Molecular Function	Protein Binding Substance P Receptor Binding	Tachykinin Receptor Activity Protein Binding
	Biological Process	Positive Regulation Of Acute Inflammatory Response Inflammatory Response Positive Regulation Of Cytosolic Calcium Ion Concentration Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Cell-cell Signaling Synaptic Transmission Insemination Long-term Memory Regulation Of Blood Pressure Associative Learning Detection Of Abiotic Stimulus Response To Hormone Negative Regulation Of Heart Rate Positive Regulation Of Epithelial Cell Migration Sensory Perception Of Pain Positive Regulation Of Synaptic Transmission, Cholinergic Positive Regulation Of Synaptic Transmission, GABAergic Response To Lipopolysaccharide Positive Regulation Of Renal Sodium Excretion Response To Morphine Positive Regulation Of Action Potential Positive Regulation Of Ossification Positive Regulation Of Saliva Secretion Response To Pain Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Corticosterone Secretion	Tachykinin Receptor Signaling Pathway Aging Positive Regulation Of Heart Rate Response To Estradiol Regulation Of Dopamine Metabolic Process Response To Cocaine Hyperosmotic Salinity Response Response To Morphine Positive Regulation Of Blood Pressure Regulation Of Feeding Behavior Positive Regulation Of Uterine Smooth Muscle Contraction
Pathways		G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Tachykinin receptors bind tachykinins Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding	G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Tachykinin receptors bind tachykinins Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Adverse response to radiation therapy ( 23719583) Response to platinum-based agents ( 22020760)
Protein-Protein Interactions		12 interactors: ARHGEF40 BAG6 CENPB FN1 MEP1A PREP TAC4 TACR1 TACR2 TACR3 TFF2 XRCC6	4 interactors: GPRASP1 TAC1 TAC3 TAC4
Entrez ID		6863	6870
HPRD ID		08876	01209
Ensembl ID		ENSG00000006128
Uniprot IDs		P20366 Q9Y494	P29371
PDB IDs		2B19 2KS9 2KSA 2KSB
Enriched GO Terms of Interacting Partners?		Tachykinin Receptor Signaling Pathway Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Saliva Secretion Regulation Of Smooth Muscle Contraction Operant Conditioning Regulation Of Saliva Secretion Hyperosmotic Salinity Response Neuropeptide Signaling Pathway Blood Circulation Positive Regulation Of Digestive System Process Positive Regulation Of Vascular Permeability Regulation Of Muscle Contraction Hyperosmotic Response Regulation Of Blood Pressure Regulation Of Vascular Permeability Response To Salt Stress Positive Regulation Of Blood Pressure Response To Morphine Regulation Of Secretion Response To Electrical Stimulus Excretion Smooth Muscle Contraction Positive Regulation Of Secretion Positive Regulation Of Acetylcholine Secretion, Neurotransmission Acute Inflammatory Response Response To Osmotic Stress Response To Ammonium Ion Positive Regulation Of Synaptic Transmission Cellular Hyperosmotic Salinity Response Smooth Muscle Contraction Involved In Micturition Intestine Smooth Muscle Contraction Negative Regulation Of Luteinizing Hormone Secretion Angiotensin-mediated Drinking Behavior Response To Abiotic Stimulus Digestion Response To Estradiol G-protein Coupled Receptor Signaling Pathway Regulation Of Acetylcholine Secretion, Neurotransmission Calcium-independent Cell-matrix Adhesion Learning Positive Regulation Of Synaptic Transmission, Cholinergic Response To Alkaloid Synaptic Transmission Prolactin Secretion Cellular Response To X-ray Negative Regulation Of Gastric Acid Secretion Negative Regulation Of Gonadotropin Secretion Micturition Response To Ozone	Tachykinin Receptor Signaling Pathway Positive Regulation Of Saliva Secretion Regulation Of Saliva Secretion Positive Regulation Of Digestive System Process Neuropeptide Signaling Pathway G-protein Coupled Receptor Catabolic Process Positive Regulation Of Corticosterone Secretion Regulation Of Blood Pressure G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Synaptic Transmission, Cholinergic Regulation Of Corticosterone Secretion Blood Circulation Regulation Of Synaptic Transmission, Cholinergic Positive Regulation Of Secretion Positive Regulation Of Action Potential Negative Regulation Of Heart Rate Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Synaptic Transmission, GABAergic Insemination Receptor Catabolic Process Regulation Of Renal Sodium Excretion Copulation Negative Regulation Of Heart Contraction Regulation Of Excretion Regulation Of Secretion Positive Regulation Of Acute Inflammatory Response Endosome To Lysosome Transport Positive Regulation Of Transport Regulation Of Synaptic Transmission, GABAergic Response To Pain Response To Morphine Positive Regulation Of Stress Fiber Assembly Lysosomal Transport Long-term Memory Positive Regulation Of Actin Filament Bundle Assembly Cell Surface Receptor Signaling Pathway Mating Positive Regulation Of Lipid Transport Regulation Of Stress Fiber Assembly Regulation Of Acute Inflammatory Response Regulation Of Heart Rate Vacuolar Transport Positive Regulation Of Epithelial Cell Migration Receptor Metabolic Process Associative Learning Multicellular Organismal Response To Stress Sensory Perception Of Pain Response To Ammonium Ion Regulation Of Lipid Transport Positive Regulation Of Inflammatory Response
Tagcloud ?		1st affymetrix barcoding capn6 comprehensively corneal corneas dystrophies dystrophy fecd fecd4 fuchs genechip hcenc hist1h3a hist1h4e hspa2 hybridized itgbl1 nalcn partek polymorphous ppcd ppcd1 prex2 scientists suite tmod1 xecd
Tagcloud (Difference) ?		1st affymetrix barcoding capn6 comprehensively corneal corneas dystrophies dystrophy fecd fecd4 fuchs genechip hcenc hist1h3a hist1h4e hspa2 hybridized itgbl1 nalcn partek polymorphous ppcd ppcd1 prex2 scientists suite tmod1 xecd
Tagcloud (Intersection) ?