SNRPD2 and GEMIN7

Number of citations of the paper that reports this interaction (PubMedID 12065586)
0

Data Source:
HPRD (in vitro)

		SNRPD2	GEMIN7
Description		small nuclear ribonucleoprotein D2 polypeptide	gem nuclear organelle associated protein 7
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U2-type Spliceosomal Complex U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex Extracellular Exosome U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal SnRNP Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies Sm-like Protein Family Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing 7-methylguanosine Cap Hypermethylation U2-type Prespliceosome Assembly	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways		snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway SARS-CoV-2 modulates host translation machinery	snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs		Artenimol
Diseases
GWAS		Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Fruit consumption ( 32066663) Subcutaneous adipose tissue ( 22589738)	Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		28 interacting genes: CEBPA CEP70 CINP DDX20 DMTN EEF1G EGFR FOXP1 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 IL7R KAT5 LSM2 LSM6 OS9 SMN1 SMN2 SNRPD1 SNRPF SPANXN2 STRAP STXBP2 STXBP3 WDR77 ZCCHC10	20 interacting genes: ADD1 CEP126 EDRF1 FEZ1 GEMIN6 GOLM1 KAT5 RN7SL1 RNU1-1 RNU2-1 RPLP1 SHC1 SMN1 SNRPB SNRPD2 SNRPD3 SNRPE STRAP TAOK1 TUBA1A
Entrez ID		6633	79760
HPRD ID		03038	07600
Ensembl ID		ENSG00000125743	ENSG00000142252
Uniprot IDs		K7ERG4 P62316	Q9H840
PDB IDs		1B34 3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6Y53 6Y5Q 7A5P 7ABG 7ABI 7B0Y 7DVQ 7EVO 7QTT 7VPX 7W59 7W5A 7W5B 8C6J 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7Q 8Q7V 8Q7W 8Q7X 8Q91 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8R7N 8RC0 8RM5 8RO2 8Y6O 8Y7E 9FMD 9GBW 9GC0 9GCL	1Y96 7BBL
Enriched GO Terms of Interacting Partners?		SMN-Sm Protein Complex Spliceosomal SnRNP Assembly SMN Complex Gemini Of Cajal Bodies Protein-RNA Complex Assembly RNA Splicing RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process Spliceosomal Complex Assembly RNA Processing MRNA Splicing, Via Spliceosome Protein-containing Complex Assembly RNA Metabolic Process Small Nuclear Ribonucleoprotein Complex Protein-containing Complex Organization Nucleic Acid Metabolic Process Nuclear Body Cytosol Cellular Component Assembly Nucleobase-containing Compound Metabolic Process U4/U6 X U5 Tri-snRNP Complex Methylosome Macromolecule Metabolic Process U2-type Precatalytic Spliceosome Nucleoplasm Tertiary Granule Spliceosomal Complex Presynaptic Dense Core Vesicle Exocytosis PICln-Sm Protein Complex Neuronal Dense Core Vesicle Exocytosis Neutrophil Degranulation Lsm2-8 Complex 7-methylguanosine Cap Hypermethylation Dense Core Granule Exocytosis Calcium Ion-regulated Exocytosis Of Neurotransmitter U6 SnRNP Nucleus RNA Binding U4 SnRNP Cajal Body Specific Granule Syntaxin-1 Binding Spliceosomal Tri-snRNP Complex Assembly Catalytic Step 2 Spliceosome DNA-templated Transcription Termination Precatalytic Spliceosome U1 SnRNP U5 SnRNP Secretory Granule Localization	SMN-Sm Protein Complex Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Protein-RNA Complex Assembly U2 SnRNP 7-methylguanosine Cap Hypermethylation U4 SnRNP Methylosome Small Nuclear Ribonucleoprotein Complex RNA Splicing, Via Transesterification Reactions U1 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex PICln-Sm Protein Complex U2-type Spliceosomal Complex Cellular Component Assembly U2-type Catalytic Step 2 Spliceosome Protein-containing Complex Assembly U7 SnRNP MRNA Splicing, Via Spliceosome U4/U6 X U5 Tri-snRNP Complex RNA Splicing Protein-containing Complex Organization SMN Complex U2-type Precatalytic Spliceosome MRNA Processing U2 SnRNP Binding Precatalytic Spliceosome RNA Methylation Telomerase Holoenzyme Complex Catalytic Step 2 Spliceosome MRNA Metabolic Process Histone Pre-mRNA DCP Binding Macromolecule Methylation RNA Modification RNA Processing Spliceosomal Complex Nuclear Body Ribonucleoprotein Complex Gemini Of Cajal Bodies Methylation Protein Targeting To Vacuole Involved In Autophagy RNA Binding Nucleic Acid Metabolic Process Telomerase RNA Binding Negative Regulation Of Supramolecular Fiber Organization Cytoskeleton Organization Cytosol Protein Methylation
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