SNRPD2 and SNRPF

Number of citations of the paper that reports this interaction (PMID 11226169)
38

Data Source:
HPRD (in vitro, two hybrid)

		SNRPD2	SNRPF
Gene Name		small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	small nuclear ribonucleoprotein polypeptide F
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome	Nucleoplasm Spliceosomal Complex U7 SnRNP U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Poly(A) RNA Binding	RNA Binding Protein Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression NcRNA Metabolic Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Gene Expression MRNA 3'-end Processing NcRNA Metabolic Process
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing snRNP Assembly mRNA Splicing - Minor Pathway Metabolism of non-coding RNA mRNA Splicing - Major Pathway	mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Metabolism of non-coding RNA mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs snRNP Assembly Processing of Capped Intronless Pre-mRNA SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		25 interactors: CEP70 CLNS1A DDX20 DMTN EEF1G EGFR GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 IL7R KAT5 LSM2 LSM6 OS9 SMN1 SMN2 SNRPD1 SNRPF STRAP STXBP2 STXBP3 WDR77 ZCCHC10	22 interactors: CLNS1A COIL DDX20 GEMIN5 GEMIN6 HOMER3 IKZF1 IL7R LNX1 LSM5 LSM6 LSM7 PSMA3 PUF60 SMN2 SNRPA1 SNRPD2 SNRPE SNRPG SRRT SRSF5 WDR77
Entrez ID		6633	6636
HPRD ID		03038	04645
Ensembl ID		ENSG00000125743
Uniprot IDs		P62316	P62306
PDB IDs		1B34 1VU2 1VU3 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3S6N 4F77	1VU2 1VU3 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3S6N 4F77
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Assembly RNA Splicing MRNA Processing Ribonucleoprotein Complex Biogenesis MRNA Metabolic Process RNA Processing NcRNA Metabolic Process Cellular Macromolecular Complex Assembly Cellular Component Assembly Gene Expression RNA Metabolic Process Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Neutrophil Degranulation Neutrophil Activation Involved In Immune Response Cellular Response To Estradiol Stimulus Neutrophil Mediated Immunity Neutrophil Activation Cellular Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Response To Estrogen Stimulus Cellular Process Leukocyte Degranulation Alkanesulfonate Metabolic Process Positive Regulation Of Platelet Aggregation Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Protein Secretion By Platelet Calcium-mediated Signaling Using Extracellular Calcium Source Interleukin-7-mediated Signaling Pathway Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Vesicle Docking Regulation Of Epithelial Cell Proliferation Actin Filament Reorganization Membrane Docking Activation Of Phospholipase A2 Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Calcium-mediated Signaling Cell Activation Exocytosis	RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis NcRNA Metabolic Process Gene Expression RNA Metabolic Process Spliceosomal Complex Assembly Cellular Macromolecular Complex Assembly Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Component Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Termination Of RNA Polymerase II Transcription Cellular Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay DNA-templated Transcription, Termination MRNA 3'-end Processing Lymph Node Development RNA 3'-end Processing Histone MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Neutrophil Differentiation Metabolic Process Interleukin-7-mediated Signaling Pathway Cellular Process Positive Regulation Of T Cell Differentiation Positive Regulation Of Lymphocyte Differentiation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of T Cell Mediated Cytotoxicity Primary MiRNA Processing Regulation Of T Cell Differentiation Positive Regulation Of NK T Cell Differentiation Aromatic Compound Catabolic Process Positive Regulation Of Granulocyte Differentiation T Cell Differentiation Regulation Of Lymphocyte Differentiation B Cell Activation
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